Zobrazeno 1 - 9
of 9
pro vyhledávání: '"B P, Bean"'
Autor:
C, Brenneis, K, Kistner, M, Puopolo, S, Jo, Dp, Roberson, M, Sisignano, D, Segal, E J, Cobos, B J, Wainger, S, Labocha, N, Ferreirós, C, von Hehn, J, Tran, G, Geisslinger, P W, Reeh, B P, Bean, C J, Woolf
Publikováno v:
British journal of pharmacology. 171(2)
Selective nociceptor fibre block is achieved by introducing the cell membrane impermeant sodium channel blocker lidocaine N-ethyl bromide (QX-314) through transient receptor potential V1 (TRPV1) channels into nociceptors. We screened local anaestheti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9034bd839ad0ec92591316879db82ca
https://pubmed.ncbi.nlm.nih.gov/24117225
https://pubmed.ncbi.nlm.nih.gov/24117225
Publikováno v:
British journal of pharmacology. 164(1)
We have developed a strategy to target the permanently charged lidocaine derivative lidocaine N-ethyl bromide (QX-314) selectively into nociceptive sensory neurons through the large-pore transient receptor potential cation channel subfamily V (TRPV1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7866ba3db8d9046be6b1bf2484816ddb
https://pubmed.ncbi.nlm.nih.gov/21457220
https://pubmed.ncbi.nlm.nih.gov/21457220
Publikováno v:
Molecular pharmacology. 46(4)
The anticonvulsant phenytoin inhibited Na+ currents in rat hippocampal neurons with a potency that increased dramatically at depolarized holding potentials, suggesting weak binding to resting Na+ channels but tight binding to open or inactivated chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a377e80b65049cf57b8d6a2d52b250fb
https://pubmed.ncbi.nlm.nih.gov/7969051
https://pubmed.ncbi.nlm.nih.gov/7969051
Publikováno v:
Molecular pharmacology. 45(1)
P-type Ca2+ channels in cerebellar Purkinje neurons and N-type Ca2+ channels in sympathetic neurons were found to be inhibited by D2 dopamine receptor antagonists with diverse structures, including phenothiazines (chlorpromazine and thioridazine), di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b5fb8c89baf2f8632a303cf799d8a85
https://pubmed.ncbi.nlm.nih.gov/8302284
https://pubmed.ncbi.nlm.nih.gov/8302284
Publikováno v:
Molecular pharmacology. 44(4)
A new peptide antagonist of voltage-activated calcium channels was purified from venom of the funnel web spider, Agelenopsis aperta. This 48-amino acid peptide, omega-agatoxin (omega-Aga)-IVB, was found to be a potent (Kd, approximately 3 nM) blocker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::448fdf98534f1a8030eee4746d1cb004
https://pubmed.ncbi.nlm.nih.gov/8232218
https://pubmed.ncbi.nlm.nih.gov/8232218
Autor:
I. M. Mintz, B. P. Bean
Publikováno v:
Dihydropyridines ISBN: 9783540573081
Voltage-dependent calcium channels are present in all neurons. They are closed at normal resting potentials, and they open when a membrane is depolarized by an action potential. One important function of calcium channels in neurons is to mediate rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bd407be3687ade872d2fc8b3b43f5a2
https://doi.org/10.1007/978-3-642-95716-1_4
https://doi.org/10.1007/978-3-642-95716-1_4
Autor:
B P, Bean
Publikováno v:
Methods in enzymology. 207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::642de49c278c7fe802430bbf602fd45d
https://pubmed.ncbi.nlm.nih.gov/1326702
https://pubmed.ncbi.nlm.nih.gov/1326702
Autor:
B P, Bean, D D, Friel
Publikováno v:
Ion channels. 2
Extracellular ATP is an activator or modulator of ionic channels in a wide variety of excitable cells. There appears to be a class of related cation-permeable ATP-activated channels in skeletal muscle, cardiac muscle, smooth muscle, and neurons; the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60bebaba8ce61091117029e2c4dc9aa1
https://pubmed.ncbi.nlm.nih.gov/1715204
https://pubmed.ncbi.nlm.nih.gov/1715204
Publikováno v:
Medizinische Monatsschrift fur Pharmazeuten. 9(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d408cd6a742dd9982c9284146b62909
https://pubmed.ncbi.nlm.nih.gov/2433568
https://pubmed.ncbi.nlm.nih.gov/2433568