Výsledky vyhledávání - "B Ole Juhnke"

Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial

Autor: Christian Hagel, Veronika Sloman, Martin Mynarek, Katharina Petrasch, Denise Obrecht, Joachim Kühl, Frank Deinlein, Renate Schmid, André O. von Bueren, Carsten Friedrich, B. Ole Juhnke, Nicolas U. Gerber, Robert Kwiecien, Hermann Girschick, Alexandra Höller, Antonia Zapf, Katja von Hoff, Stefan Rutkowski

Publikováno v: Hagel, C, Sloman, V, Mynarek, M, Petrasch, K, Obrecht, D, Kühl, J, Deinlein, F, Schmid, R, von Bueren, A O, Friedrich, C, Juhnke, B O, Gerber, N U, Kwiecien, R, Girschick, H, Höller, A, Zapf, A, von Hoff, K & Rutkowski, S 2022, ' Refining M1 stage in medulloblastoma : criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial ', European journal of cancer (Oxford, England : 1990), vol. 164, pp. 30-38 . https://doi.org/10.1016/j.ejca.2021.12.032

BACKGROUND: Medulloblastoma is the most common malignant paediatric brain tumour, and cerebrospinal fluid (CSF) dissemination (M1 stage) is a high-risk prognostic factor. Criteria for CSF evaluation and for differentiating M0 from M1 stage are not cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2606ca2650132764c9c0988e3fa4347
https://doi.org/10.1016/j.ejca.2021.12.032

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Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial

Autor: Carsten Friedrich, André O. von Bueren, Christine Haberler, Brigitte Bison, B-Ole Juhnke, Beate Timmermann, Marcel Kool, Robert Kwiecien, Nicolas U. Gerber, Torsten Pietsch, Stefan M. Pfister, Marco Gessi, Katja von Hoff, Monika Warmuth-Metz, Martin Mynarek, Rolf-Dieter Kortmann, Ulrich Schüller, Stefan Rutkowski, Claudia Spix

Publikováno v: Neuro Oncol
Juhnke, B-O, Gessi, M, Gerber, N U, Friedrich, C, Mynarek, M, von Bueren, A O, Haberler, C, Schüller, U, Kortmann, R-D, Timmermann, B, Bison, B, Warmuth-Metz, M, Kwiecien, R, Pfister, S M, Spix, C, Pietsch, T, Kool, M, Rutkowski, S & von Hoff, K 2022, ' Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial ', Neuro-Oncology, vol. 24, no. 1, pp. 127-137 . https://doi.org/10.1093/neuonc/noab100
Neuro-oncology (2021)

Background Embryonal tumors with multilayered rosettes (ETMR) are highly aggressive tumors occurring in early childhood. Published clinical data refer to retrospective, heterogeneously treated cohorts. Here, we describe the outcome of patients treate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0967be33affa38e8991c236708f92a00
https://europepmc.org/articles/PMC8730753/

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Therapeutic Implications of Improved Molecular Diagnostics for Rare CNS-Embryonal Tumor Entities: Results of an International, Retrospective, Observational Study

Autor: Katja von Hoff, Christine Haberler, Felix Schmitt-Hoffner, Elizabeth Schepke, Teresa de Rojas, Sandra Jacobs, Michal Zapotocky, David Sumerauer, Marta Perek-Polnik, Christelle Dufour, Dannis von Vuurden, Irene Slavc, Johannes Gojo, Jessica C. Pickles, Nicolas U. Gerber, Maura Massimino, Maria Joao Gil-da-Costa, Miklos Garami, Ella Kumirova, Astrid Sehested, David Scheie, Ofelia Cruz, Lucas Moreno, Jaeho Cho, Bernward Zeller, Niels Bovenschen, Michael Grotzer, Daniel Alderete, Matija Snuderl, Olga Zheludkova, Andrey Golanov, Konstantin Okonechnikov, Martin Mynarek, B. Ole Juhnke, Stefan Rutkowski, Ulrich Schüller, Barry Pizer, Barbara von Zezschwitz, Robert Kwiecien, Maximilian Wechsung, Frank Konietschke, Eugene I. Hwang, Dominik Sturm, Stefan M. Pfister, Andreas von Deimling, Elisabeth J. Rushing, Marina Ryzhova, Peter Hauser, Maria Lastowska, Pieter Wesseling, Felice Giangaspero, Cynthia Hawkins, Dominique Figarella-Branger, Charles Eberhardt, Peter Burger, Marco Gessi, Andrey Korshunov, Tom S. Jacques, David Capper, Torsten Pietsch, Marcel Kool

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50e721e6a8ba221b74c3f143e27c15fe
https://doi.org/10.2139/ssrn.3830355

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EPEN-39. CLINICAL STRATIFIED TREATMENT OF LOCALIZED PEDIATRIC INTRACRANIAL EPENDYMOMA WITH COMBINED LOCAL IRRADIATION AND CHEMOTHERAPY WITHIN THE PROSPECTIVE, MULTICENTER E-HIT TRIAL – THE MOLECULAR SUBGROUP MATTERS

Publikováno v: Neuro-Oncology

BACKGROUND Pediatric ependymoma is a heterogenous disease. Subgroup-specific clinical information on prospectively treated patients will help to improve treatment stratification. METHODS Within the population based, prospective, multicenter E-HIT-tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009fb9719414196b6d1b26b507973c71
http://europepmc.org/articles/PMC7715574

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PATH-07. QUALITY ASSURANCE IN CEREBROSPINAL FLUID CYTOLOGY ASSESSMENT FOR MEDULLOBLASTOMA STAGING LEADS TO POTENTIAL IMPROVED RISK-GROUP ASSESSMENT IN THE PROSPECTIVE MULTICENTER HIT-2000 TRIAL

Autor: Nicolas U. Gerber, Carsten Friedrich, Robert Kwiecien, Renate Schmid, Frank Deinlein, Alexandra Höller, Stefan Rutkowski, Katja von Hoff, Christian Hagel, Antonia Zapf, Hermann Girschick, Denise Obrecht, Veronika Sloman, André O. von Bueren, B Ole Juhnke, Martin Mynarek, Katharina Petrasch

Publikováno v: Neuro-Oncology

BACKGROUND Cerebrospinal fluid (CSF) dissemination of medulloblastoma (M1 stage) is a high-risk prognostic factor. However, because diagnostic criteria for M1 staging are missing we specified process-related and cytomorphological parameters influenci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afd5d8efb04d7ade9f2e6edf1136cf6
https://doi.org/10.1093/neuonc/noaa222.643

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MBCL-09. ISOLATED M1 METASTASES IN PEDIATRIC MEDULLOBLASTOMA: IS POSTOPERATIVE RADIOTHERAPY FOLLOWED BY MAINTENANCE CHEMOTHERAPY SUPERIOR TO POSTOPERATIVE SANDWICH-CHEMOTHERAPY AND RADIOTHERAPY?

Publikováno v: Neuro-Oncology

BACKGROUND Impact of isolated spread into the cerebrospinal fluid (CSF) is still not investigated comprehensively for childhood medulloblastoma and the best therapeutic strategy is currently unclear. MATERIAL AND METHODS Sixty-six patients with isola

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ec3aa86415eff38057f995cdcec9f4
https://doi.org/10.1093/neuonc/noaa222.485

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EPEN-09. IMPACT OF MOLECULAR SUBGROUP ON OUTCOME FOR INFANTS <12 MONTHS WITH INTRACRANIAL EPENDYMOMA - GERMAN EXPERIENCE FROM HIT2000, INTERIM-2000-REGISTRY AND I-HIT-MED REGISTRY

Autor: Kristian W. Pajtler, Dominik Sturm, Rolf-Dieter Kortmann, Monika Warmuth-Metz, Martin Benesch, Brigitte Bison, Stefan Rutkowski, Nicolas U. Gerber, Ulrich Schüller, Felix Sahm, Katja von Hoff, B Ole Juhnke, Martin Mynarek, Andreas von Deimling, Hendrik Witt, Torsten Pietsch, Denise Obrecht, Beate Timmermann, Stefan M. Pfister

Publikováno v: Neuro-Oncology

BACKGROUND For infant ependymoma (EP), decision for radiotherapy during first-line therapy is a dilemma. We analyzed therapy outcomes of EP patients younger than 12 months at diagnosis according to molecular subgroup. PATIENTS AND METHODS Between 200

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d3657d09eb182ba86b8c53375fdc38
https://doi.org/10.1093/neuonc/noaa222.149

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MBCL-06. RISK STRATIFICATION IMPROVEMENT OF THE HIT2000 AND I-HIT-MED COHORTS USING MOLECULAR SUBTYPES I-VIII OF GROUP 3/4 MEDULLOBLASTOMAS

Autor: Martin Sill, Torsten Pietsch, Katja von Hoff, Jonas Ecker, Felix Sahm, B Ole Juhnke, Stefan Rutkowski, Andreas von Deimling, Till Milde, Dominic Sturm, Ulrich Schüller, Martin Mynarek, Michael Bockmayr, Olaf Witt, David T.W. Jones, Denise Obrecht, Florian Selt, Stefan M. Pfister

Publikováno v: Neuro-Oncology

OBJECTIVE Molecular subtypes of Group 3/4 medulloblastoma have been identified by unsupervised clustering methods in different studies. We hypothesized that risk stratification using these subtypes I-VIII improves outcome prediction. PATIENTS AND MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e071cf98daa709fbd2064f6e57a58adf
https://doi.org/10.1093/neuonc/noaa222.482

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Hirntumoren im Kindes- und Jugendalter

Autor: Hendrik Witt, RD Kortmann, Michael C. Frühwald, Brigitte Bison, B Ole Juhnke, Stefan Rutkowski

Publikováno v: Der Onkologe. 22:908-922

In den letzten Jahren wurden in vielen Disziplinen der padiatrischen Neuroonkologie neue Erkenntnisse generiert. Dazu zahlen wichtige Fortschritte zum Verstandnis der Biologie von Medulloblastom, Ponsgliom, niedrig- und hochgradigem Gliom, Ependymom,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d20b4aa579b5738f532c8cb241a0be
https://doi.org/10.1007/s00761-016-0127-0

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