Zobrazeno 1 - 10
of 19
pro vyhledávání: '"B Nicolás Díaz-Chico"'
Autor:
Antonio Cabrera de León, Luis Alberto Henríquez-Hernández, Santiago Domínguez-Coello, Delia Almeida-González, Buenaventura Brito-Díaz, Adolfo Murias-Rosales, Armando Aguirre-Jaime, B. Nicolás Díaz-Chico, M. del Cristo Rodríguez-Pérez, Ana González-Hernández
Publikováno v:
The International Journal of Biological Markers. 27:219-226
Background The sequences of many human genes that encode proteins involved in cancer contain polymorphic microsatellites. Variations in microsatellite length may constitute risk factors in several human diseases, a possibility that has been little ex
Autor:
Juan C. Díaz-Chico, F. Germán Rodríguez, B. Nicolás Díaz-Chico, Raquel Ramírez, Domingo Navarro, Ricardo Chirino, Ana González, A. Cabrera de León, Cristina Bilbao, A. Aguirre Jaime
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 105:1-15
Aromatase (CYP19) converts adrenal and ovarian androgens into estrogens, which supports the growth of estrogen-dependent breast cancers. Anti-aromatase agents are displacing antiestrogens as the first-line treatment for estrogen receptor positive bre
Autor:
Germán Rodríguez, Cristina Bilbao, Raquel Ramírez, Orlando Falcón, Laureano León, Ricardo Chirino, B. Pilar Díaz, Juan F. Rivero, Manuel Perucho, B. Nicolás Díaz-Chico, Juan C. Díaz-Chico
Publikováno v:
International Journal of Cancer. 118:1420-1425
The human androgen receptor (AR) gene possesses 2 trinucleotide repeats of CAG and GGN in exon 1. The CAG repeat corresponds to a polyglutamine tract in the N-terminal region of the receptor, that affects its transcriptional efficiency. The GGN repea
Publikováno v:
Revista de Oncología. 4:228-240
Carcinoma of the prostate is the most frequently diagnosed malignancy and the second leading cause of death as a result of cancer in men in the Western countries. Androgens act on the prostatic epithelial cells by binding to an intracellular protein,
Autor:
B. Nicolás Díaz Chico, Antonio Cabrera de León, Buenaventura Brito Díaz, Ana González Hernández, Delia Almeida González, María del Cristo Rodríguez Pérez
Publikováno v:
Immunology letters. 133(1)
Autoimmune diseases occur more in women than in men, and this may be attributable to the role of estrogens. Androgens promote autoimmune diseases with a profile of type 1 cytokines, such as rheumatoid arthritis, whereas estrogens promote autoimmune d
Autor:
Safira Delgado-Guerra, Rafael Arteaga-Ortiz, Ignacio Ara, Teresa Fuentes, Amelia Guadalupe-Grau, Cecilia Dorado, Germán Vicente-Rodríguez, Borja Guerra, F Germán Rodríguez-González, Hugo Olmedillas, Jorge Pérez-Gómez, B Nicolás Díaz-Chico, Jose A. L. Calbet
Publikováno v:
British journal of sports medicine. 45(2)
The exon-1 of the androgen receptor (AR) gene contains two repeat length polymorphisms which modify either the amount of AR protein inside the cell (GGN(n), polyglycine) or its transcriptional activity (CAG(n), polyglutamine). Shorter CAG and/or GGN
Autor:
Cristina Bilbao, Pedro C. Lara, Laura López-Ríos, Patricia Barber Pérez, B. Nicolás Díaz-Chico, Germán Rodríguez-González, Juan C. Díaz-Chico, Ricardo Chirino, Lluis Serra-Majem, Raquel Ramírez-Moreno
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 113(3-5)
The human androgen receptor (AR) gene possesses two trinucleotide repeats of CAG and GGN in exon-1. The GGN repeat affects the amount of AR protein translated, while the CAG repeat affects the efficiency of AR transcriptionaly. In this study, we have
Autor:
Cristina Bilbao, B. Nicolás Díaz-Chico, Germán Rodríguez-González, Saúl Cabrera, Juan C. Díaz-Chico, Nicolás Chesa, Lluis Serra, J. Cabrera, Raquel Ramírez-Moreno
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 113(1-2)
The exon 1 of the human androgen receptor (AR) gene contains two length polymorphisms of CAG (polyglutamine) and GGN (polyglycine). “In vitro” experiments suggest that the larger GGN repeats provide a lower AR-protein yield, whereas the larger CA
Autor:
F. Javier Dorta, Armando Aguirre-Jaime, Ricardo Reyes, Antonio Noda Cabrera, Ana González, Germán Rodríguez, B. Nicolás Díaz-Chico, Juan C. Díaz-Chico, Buenaventura Brito, Ma del Cristo Rodríguez
Publikováno v:
European journal of cancer (Oxford, England : 1990). 43(16)
The exon 1 of the human androgen receptor gene (AR) contains both CAG (polyglutamine) and GGN (polyglycine) repeat length polymorphisms. Large CAG repeats have been related to an increased risk of breast cancer (BC), whereas the influence of the GGN
Autor:
Domingo Navarro Bosch, B. Nicolás Díaz Chico, Juan Carlos Díaz Chico, Eduardo Escrich Escriche
Publikováno v:
Selective Estrogen Receptor Modulators ISBN: 9783540242277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::701ddeb4c01babe2023fd2d8c1a9bfe8
https://doi.org/10.1007/3-540-34742-9_1
https://doi.org/10.1007/3-540-34742-9_1