Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease

Autor: Tim Elliott, B N Hudspith, Liljana Petrovska, Michael B. Cooley, Jeremy D. Sanderson, Clifton K. Fagerquist, Robert E. Mandrell, Luke P. Randall, Alex Boussioutas, Guanghui Wu, Jonathan Brostoff, Gareth Parkes, Beatriz Quiñones, Neil B. Rayment

Publikováno v: Inflammatory bowel diseases. 19(11)

BACKGROUND Mucosa-associated Escherichia coli are abundant in inflammatory bowel disease (IBD), but whether these bacteria gain intracellular access within the mucosa is uncertain. If E. coli does gain intracellular access, the contribution of bacter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb95524f5b13677955770ff7ee47979e
https://pubmed.ncbi.nlm.nih.gov/23989750

Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome

Autor: G C, Parkes, N B, Rayment, B N, Hudspith, L, Petrovska, M C, Lomer, J, Brostoff, K, Whelan, J D, Sanderson

Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 24(1)

There is increasing evidence to support a role for the gastrointestinal microbiota in the etiology of irritable bowel syndrome (IBS). Given the evidence of an inflammatory component to IBS, the mucosa-associated microbiota potentially play a key role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::046e96a9376b47ce666acb4f2eef0770
https://pubmed.ncbi.nlm.nih.gov/22070725

In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes

Autor: H. van Loveren, Sander W. Spiekstra, Rob J. Vandebriel, Clive Meredith, B. N. Hudspith

Publikováno v: Vandebriel, RJ, Spiekstra, SW, Hudspith, BN, Meredith, C & Van Loveren, H 1999, ' In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes ', Toxicology, vol. 135, no. 1, pp. 49-66 .
Toxicology, 135(1), 49-66. Elsevier Ireland Ltd

Rat thymocytes and splenocytes were exposed in vitro to the model compounds Cyclosporin A (CsA), an immunosuppressive drug, and bis(tri-n-butyltin)oxide (TBTO), an immunotoxic environmental contaminant. The lymphocyte transformation test (LTT), cytok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e68693af5ce78aafb808fb64edf21d0
https://research.vumc.nl/en/publications/44091531-ab21-48e9-8953-d3eb24e26e9e

The effect of MMMF on the kinetics of cytokine expression in murine lung populations: Role in fibre-induced disease

Autor: K. Miller, C. Meredith, B. N. Hudspith

Publikováno v: Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres ISBN: 9783642790430

Our knowledge concerning mineral fibre induced disease has increased over the last few decades due to the intensive research effort in this area. Based upon expert clinical observations, extensive epidemiological studies and the use of experimental s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d6bfc8e222b6092a16f62edbcec56e2
https://doi.org/10.1007/978-3-642-79041-6_7

PP-007 Defective in vitro macrophage maturation in Crohn's disease

Autor: B N Hudspith, N B Rayment, T Elliott, J Brostoff, J D Sanderson

Publikováno v: Gut. 59:A42.3-A43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::345f45c25db92ca4a6f61cde0c3cbb57
https://doi.org/10.1136/gut.2009.208991y