Zobrazeno 1 - 4
of 4
pro vyhledávání: '"B N, Ford"'
Publikováno v:
Radiation Research. 156:668-671
Individual differences in response to radiation are well known, but the molecular basis for these differences is not well understood, and molecular indicators that are useful in assessing individual variation are lacking. Cells from patients developi
Publikováno v:
Environmental and molecular mutagenesis. 36(3)
A significant fraction of human cancers are thought to have a genetic component and several lines of evidence suggest that deficiencies in DNA repair may be a contributing factor. Little is known, however, about the frequency and distribution of vari
Publikováno v:
Environmental and molecular mutagenesis. 36(3)
Genotoxic stresses induce cellular responses that can be observed at the level of gene expression. We have studied changes in gene expression following BPDE exposure in HeLa cells by using a cDNA expression array of 597 human genes. After a 53-hr exp
Publikováno v:
Environmental and molecular mutagenesis. 33(1)
DNA repair systems act to maintain genome integrity in the face of replication errors, environmental insults, and the cumulative effects of age. More than 70 human genes directly involved in the five major pathways of DNA repair have been described,