Zobrazeno 1 - 10
of 79
pro vyhledávání: '"B N, Fields"'
Autor:
M N Rozinov, B N Fields
Publikováno v:
Journal of Virology. 68:6667-6671
Following infection by pairs of reovirus isolates consisting of combinations of reovirus T1 Lang, T2 Jones, or T3 Dearing, we found that one of the isolates interfered with the yield of progeny RNA derived from the other parents. The most significant
Publikováno v:
Journal of Virology. 68:6458-6465
A panel of serotype 3 (T3) reovirus strains was screened to determine their relative capacities to cause lethal infection and hepatobiliary disease following peroral inoculation in newborn mice. A wide range of 50% lethal doses (LD50s) was apparent a
Publikováno v:
Journal of Virology. 67:3019-3026
We examined pathogenic characteristics of plaque-purified reoviruses isolated from persistently infected L-cell cultures (PI viruses) after intracranial inoculation into newborn mice. The PI viruses were isolated from independent cultures initiated w
Autor:
B N Fields, David R. Wessner
Publikováno v:
Journal of Virology. 67:2442-2447
To better understand the mechanism(s) by which viruses respond to chemical or physical treatments, we isolated a series of mutant strains of reovirus type 3 Dearing that exhibit increased ethanol resistance. Following exposure to 33% ethanol for 20 m
Autor:
Max L. Nibert, B N Fields
Publikováno v:
Journal of Virology. 66:6408-6418
Penetration of a cell membrane as an early event in infection of cells by mammalian reoviruses appears to require a particular type of viral particle, the infectious subvirion particle (ISVP), which is generated from an intact virion by proteolytic c
Publikováno v:
Journal of Clinical Investigation. 88:727-734
Publikováno v:
Journal of Clinical Investigation. 87:1628-1633
Viral growth in specific tissue is usually required in order to lead to pathology. Two reovirus isolates (type 1 Lang and type 3 Dearing) differ in their capacity to grow in cultured mouse heart cells. The mammalian reoviruses contain a genome of 10
Publikováno v:
Journal of Virology. 65:123-131
Penetration of the nervous systems of suckling mice by prototype strains of the three mammalian reovirus serotypes was studied after footpad inoculation of a dose (10(7) PFU) representing 3.5 x 10(3) 50% lethal doses (LD50) for reovirus type 3 Dearin
Publikováno v:
Journal of Virology. 64:2976-2989
This report describes a model for the structure of the reovirus cell-attachment protein sigma 1. S1 gene nucleotide sequences were determined for prototype strains of the three serotypes of mammalian reoviruses. Deduced amino acid sequences of the S1
Autor:
B N Fields, Jay W. Hooper
Publikováno v:
Journal of virology. 70(1)
Reovirus intermediate subviral particles (ISVPs) but not intact virions or cores have been shown to possess the capacity to permeabilize mouse L cells as determined by a 51Cr release assay. We used monoclonal antibodies (MAbs) directed against protei