Zobrazeno 1 - 3
of 3
pro vyhledávání: '"B N, Chau"'
Autor:
Thomas Bertero, Katherine A Cottrill, Yu Lu, Sofia Annis, Andrew Hale, Adrienn Krauszman, Balkrishen Bhat, Rajan Saggar, Rajeev Saggar, W. D Wallace, David J Ross, Sara O Vargas, Brian B Graham, Rahul Kumar, Stephen M Black, Sohrab Fratz, Jeffrey R Fineman, James D West, Kathleen J Haley, Aaron B Waxman, Wolfgang M Kuebler, B. N Chau, Stephen Y Chan
Publikováno v:
Circulation. 130
Background: Pulmonary hypertension (PH) is a deadly vascular disease with enigmatic molecular origins. Facets of PH have been characterized in isolation, but many have yet to be unified by a common upstream regulator. Methods & Results: We constructe
Antiapoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-Mediated Conversion to Proapoptotic Proteins
Publikováno v:
Journal of Virology. 74:5024-5031
The antiapoptotic Bcl-2 and Bcl-x L proteins of mammals are converted into potent proapoptotic factors when they are cleaved by caspases, a family of apoptosis-inducing proteases (E. H.-Y. Cheng, D. G. Kirsch, R. J. Clem, R. Ravi, M. B. Kastan, A. Be
Publikováno v:
Molecular cell. 6(1)
Bcl-x(L), an antiapoptotic Bcl-2 family member, is postulated to function at multiple stages in the cell death pathway. The possibility that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway is supported by this rep