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Autor:
M J, Millward, L K, Webster, D, Rischin, K H, Stokes, G C, Toner, J F, Bishop, I N, Olver, B M, Linahan, M E, Linsenmeyer, D M, Woodcock
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)
Cremophor EL (cremophor), a component of the paclitaxel formulation, can potentially reverse P-glycoprotein-associated multidrug resistance. A Phase I trial of cremophor as a 6-h infusion every 3 weeks was performed with bolus doxorubicin (50 mg/m2).