Zobrazeno 1 - 10
of 26
pro vyhledávání: '"B M, Kumpel"'
Autor:
B. M. Kumpel
Publikováno v:
ISBT Science Series. 7:68-71
Pregnancy is an “immunological Paradox”. This is because pregnant women are tolerant of their semi-allogeneic fetus but are not immunosuppressed and indeed make strong antibody responses. The immunological changes required are driven mainly by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9846f97c3b936e7079c069f5883e7008
https://doi.org/10.1111/j.1751-2824.2012.01568.x
https://doi.org/10.1111/j.1751-2824.2012.01568.x
Autor:
B. M. Kumpel, Maria Manoussaka
Publikováno v:
Vox Sanguinis. 102:2-12
During pregnancy, women are tolerant of their semi-allogeneic fetus whilst not being immunosuppressed and indeed readily form alloantibodies. This 'Immunological Paradox of Pregnancy' may be explained by an understanding of placental anatomy and immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69630c266032174223e6e7a1474652c4
https://doi.org/10.1111/j.1423-0410.2011.01533.x
https://doi.org/10.1111/j.1423-0410.2011.01533.x
Autor:
B. M. Kumpel
Publikováno v:
Clinical and Experimental Immunology. 154:1-5
Summary For 40 years prophylactic anti-D has been given to D-negative women after parturition to prevent haemolytic disease of the fetus and newborn. Monoclonal or recombinant anti-D may provide alternatives to the current plasma-derived polyclonal I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bf8003c674e6319ad133717a43be25
https://doi.org/10.1111/j.1365-2249.2008.03735.x
https://doi.org/10.1111/j.1365-2249.2008.03735.x
Autor:
B. M. Kumpel
Publikováno v:
Vox Sanguinis. 93:99-111
Prophylactic anti-D is a very safe and effective therapy for the suppression of D-immunization and prevention of haemolytic disease of the foetus and newborn. The primary mode of action of anti-D is rapid clearance of fetal D-positive red cells from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eba377f52afccf5dbedffd2de55f903
https://doi.org/10.1111/j.1423-0410.2007.00945.x
https://doi.org/10.1111/j.1423-0410.2007.00945.x
Autor:
B. M. Kumpel
Publikováno v:
ISBT Science Series. 2:75-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296e55fdf81204fd683d4734fae816eb
https://doi.org/10.1111/j.1751-2824.2007.00063.x
https://doi.org/10.1111/j.1751-2824.2007.00063.x
Publikováno v:
Transfusion medicine (Oxford, England). 23(3)
Fetomaternal haemorrhage (FMH) assessment by the Kleihauer-Betke test (KBT) is rapid but semi-quantitative and liable to false positive results.To compare FMH estimated by KBT with flow cytometry (FC) quantitation for 37 patients with massive FMH, ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5798100cffcb99f3b335a08eb9b01e5
https://pubmed.ncbi.nlm.nih.gov/23578132
https://pubmed.ncbi.nlm.nih.gov/23578132
Autor:
S. R. Sooranna, B. M. Kumpel
Publikováno v:
Transfusion Medicine. 6:115-120
Placental trophoblast cells were cultured on filters that allow access to medium bathing the apical and basal surfaces of cells. Purified human IgG was added to either the apical or the basal chambers and sampled at intervals of up to 100min for dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b039d0fe450f0ce5d359dafa7c7529f
https://doi.org/10.1046/j.1365-3148.1996.d01-59.x
https://doi.org/10.1046/j.1365-3148.1996.d01-59.x
Publikováno v:
Transfusion. 36:432-437
BACKGROUND: Determination of the volume of fetal D-positive cells in the circulation of D-negative women after delivery is carried out to determine whether additional prophylactic anti-D should be given to the mother. Although the Kleihauer-Betke tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4737f3215ddb4f5b2f5511e066a744f
https://doi.org/10.1046/j.1537-2995.1996.36596282587.x
https://doi.org/10.1046/j.1537-2995.1996.36596282587.x
Autor:
B. M. Kumpel
Publikováno v:
European Journal of Immunogenetics. 17:321-330
Anti-D and anti-c monoclonal antibodies (MABS) were found to be heterogeneous with respect to their activity in five cell-mediated functional assays. The two IgG3 MABS promoted greater rosette formation of red cells with monocytes than the IgG1 MABS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa51c2891f3f93085d693f2de74deb7c
https://doi.org/10.1111/j.1744-313x.1990.tb00883.x
https://doi.org/10.1111/j.1744-313x.1990.tb00883.x
Autor:
GF Lucas, Peter Soothill, Christopher J. Elson, D. J. Jackson, Michael F. Murphy, B. M. Kumpel
Publikováno v:
Clinical and experimental immunology. 142(1)
Summary The human platelet antigen-1a (HPA-1a) is the most common alloantigenic target in fetal and neonatal alloimmune thrombocytopenia (NAIT). Treatment currently depends on the outcome in previous pregnancies. HPA-1 specific T cell responses were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55249b4775cc18fadd4779555e8d130d
http://ora.ox.ac.uk/objects/uuid:d6c4903d-0454-4022-a02c-f0a3c3801f2c
http://ora.ox.ac.uk/objects/uuid:d6c4903d-0454-4022-a02c-f0a3c3801f2c