Zobrazeno 1 - 10
of 11
pro vyhledávání: '"B L, West"'
Autor:
M. F. Vincent, J. A. Berkner, Frank V. Bright, and Charles L. Liotta, B. L. West, Sergei G. Kazarian, Charles A. Eckert
Publikováno v:
The Journal of Physical Chemistry B. 102:2176-2186
Supercritical fluid chromatography is a powerful technique for analysis, and it also provides a useful tool for the measurement of thermodynamic properties. For any application, the method involves equilibration between the mobile supercritical fluid
Autor:
R C, Ribeiro, J W, Apriletti, R L, Wagner, B L, West, W, Feng, R, Huber, P J, Kushner, S, Nilsson, T, Scanlan, R J, Fletterick, F, Schaufele, J D, Baxter
Publikováno v:
Recent progress in hormone research. 53
This review summarizes the studies conducted in our laboratory on the mechanisms of thyroid hormone action over the past two decades. We have attempted to place our studies on thyroid hormone receptors (TRs) in perspective with the work conducted by
Publikováno v:
The Journal of biological chemistry. 267(21)
The intact human growth hormone (hGH) gene is negatively regulated by triiodothyronine (T3) treatment in transfected rat pituitary tumor cells. We now demonstrate that this responsiveness is mediated by a negative thyroid hormone response element (nT
Publikováno v:
The Journal of biological chemistry. 266(18)
The gene encoding rabbit muscle creatine kinase (CK) has been subcloned into a single plasmid, and the protein expressed in a soluble and functional form in Escherichia coli. The amino terminus, specific activity, and electrophoretic mobility of the
Identification of a tumor necrosis factor-responsive element in the tumor necrosis factor alpha gene
Publikováno v:
The Journal of biological chemistry. 266(15)
The regulation by tumor necrosis factor alpha (TNF) of its own promoter has been investigated by transient transfection and nuclear protein binding assays. In human K652 erythroleukemia cells TNF produced an 8-10-fold activation of the human TNF prom
Publikováno v:
The Journal of biological chemistry. 265(28)
A DNA-binding factor present in a wide variety of cell types is shown to bind to a site (GHF2) within the rat growth hormone gene promoter between nucleotides -147 and -129. Biochemical and transcriptional properties identify this factor as Sp1. The
Publikováno v:
The Journal of biological chemistry. 265(24)
DNase I footprinting identifies a tissue-general factor, GHF3, binding to the rat growth hormone promoter between nucleotides -239 and -219. Mutation of the GHF3-binding site reduces promoter activity to 30% of that of the wild-type promoter after tr
Publikováno v:
Transfusion. 26:136-140
In order to investigate collection of committed hematopoietic progenitor cells (CFU-GM) by hemapheresis, four protocols using a discontinuous cell separator (Haemonetics) were evaluated. The combined platelet and granulocytapheresis procedure using h
Publikováno v:
The Journal of biological chemistry. 264(11)
Elements controlling tissue-specific expression of the human atrial natriuretic factor gene have been examined in primary cultures of neonatal rat cardiocytes. When a 68-base pair fragment from human atrial natriuretic factor (hANF) 5'-flanking seque
Publikováno v:
The Journal of biological chemistry. 264(20)
The thyroid hormone receptor exerts transcriptional control over a variety of genes. This report describes four sites that bind this receptor with high affinity within the 5'-flanking DNA of the rat growth hormone gene, approximately centered at -180