Výsledky vyhledávání - "B L, Vaisman"

Akademický článek

Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits: LDL metabolism and HDL metabolism are affected in a gene dose-dependent manner

Autor: M E Brousseau, S Santamarina-Fojo, B L Vaisman, D Applebaum-Bowden, A M Bérard, G D Talley, H B Brewer, Jr, J M Hoeg

Publikováno v: Journal of Lipid Research, Vol 38, Iss 12, Pp 2537-2547 (1997)

Lecithin:cholesterol acyltransferase (LCAT) is an enzyme well known for its involvement in the intravascular metabolism of high density lipoproteins; however, its role in the regulation of apolipoprotein (apo) B-containing lipoproteins remains elusiv

Externí odkaz: https://doaj.org/article/b352b7ce0aec4d8b8c8838cdea68e5bb

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Akademický článek

Adenovirus-mediated expression of hepatic lipase in LCAT transgenic mice

Autor: K A Dugi, B L Vaisman, N Sakai, C L Knapper, S M Meyn, H B Brewer, Jr, S Santamarina-Fojo

Publikováno v: Journal of Lipid Research, Vol 38, Iss 9, Pp 1822-1832 (1997)

In order to evaluate the coordinate role that hepatic lipase (HL) and lecithin:cholesterol acyltransferase (LCAT) play in modulating HDL particle heterogeneity and function in vivo we utilized recombinant adenovirus to express HL in control and LCAT

Externí odkaz: https://doaj.org/article/056c9c361c5c4141b003f30aefc40f69

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Correction of hypoalphalipoproteinemia in LDL receptor-deficient rabbits by lecithin:cholesterol acyltransferase

Autor: M E, Brousseau, J, Wang, S J, Demosky, B L, Vaisman, G D, Talley, S, Santamarina-Fojo, H B, Brewer, J M, Hoeg

Publikováno v: Journal of lipid research. 39(8)

Familial hypercholesterolemia (FH), a disease caused by a variety of mutations in the low density lipoprotein receptor (LDLr) gene, leads not only to elevated LDL-cholesterol (C) concentrations but to reduced high density lipoprotein (HDL)-C and apol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44c72a63a873a358d9e9a6b34e59a24c
https://pubmed.ncbi.nlm.nih.gov/9717715

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Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits: LDL metabolism and HDL metabolism are affected in a gene dose-dependent manner

Autor: M E, Brousseau, S, Santamarina-Fojo, B L, Vaisman, D, Applebaum-Bowden, A M, Bérard, G D, Talley, H B, Brewer, J M, Hoeg

Publikováno v: Journal of lipid research. 38(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1b69d7fc2b32dee6dcef1473f86aa34
https://pubmed.ncbi.nlm.nih.gov/9458277

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Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency

Autor: N, Sakai, B L, Vaisman, C A, Koch, R F, Hoyt, S M, Meyn, G D, Talley, J A, Paiz, H B, Brewer, S, Santamarina-Fojo

Publikováno v: The Journal of biological chemistry. 272(11)

We have established a mouse model for human LCAT deficiency by performing targeted disruption of the LCAT gene in mouse embryonic stem cells. Homozygous LCAT-deficient mice were healthy at birth and fertile. Compared with age-matched wild-type litter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ef617f70409339e4ffe39b5050f08c9
https://pubmed.ncbi.nlm.nih.gov/9054454

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