Zobrazeno 1 - 10
of 36
pro vyhledávání: '"B L, Roth"'
Autor:
M, Salaga, P R, Polepally, M, Zielinska, M, Marynowski, A, Fabisiak, N, Murawska, K, Sobczak, M, Sacharczuk, J C, Do Rego, B L, Roth, J K, Zjawiony, J, Fichna
Publikováno v:
British journal of pharmacology. 172(17)
The opioid system plays a crucial role in several physiological processes in the CNS and in the periphery. It has also been shown that selective opioid receptor agonists exert potent inhibitory action on pruritus and pain. In this study we examined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ea9fa5ad00866dddb2834b4740e1b76
https://pubmed.ncbi.nlm.nih.gov/26040667
https://pubmed.ncbi.nlm.nih.gov/26040667
Autor:
B. L. Roth, Gary A. Gudelsky, J. F. Nash, Xuemei Huang, David E. Nichols, Danuta Marona-Lewicka, Stewart Frescas
Publikováno v:
Journal of Medicinal Chemistry. 37:4346-4351
A method was found to synthesize 1-(2,5-dimethoxy-4-(trifluoromethyl) phenyl)-2-aminopropane, 5, and its des-alpha-methyl congener 2-(2,5-dimethoxy-4-(trifluoromethyl)phenyl)aminoethane, 6, the trifluoromethyl analogs of substituted hallucinogenic ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634d570ef5caf6a8b03b0451836223bb
https://doi.org/10.1021/jm00051a011
https://doi.org/10.1021/jm00051a011
Autor:
B, Karolewicz, K, Szebeni, C A, Stockmeier, L, Konick, J C, Overholser, G, Jurjus, B L, Roth, G A, Ordway
Publikováno v:
Journal of neurochemistry. 91(5)
Disruptions of glutamatergic and noradrenergic signaling have been postulated to occur in depressive disorders. Glutamate provides excitatory input to the noradrenergic locus coeruleus (LC). In this study, the location of immunoreactivity against neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e65c2df10eab15ddfc2c9f443c6cb18e
https://pubmed.ncbi.nlm.nih.gov/15569249
https://pubmed.ncbi.nlm.nih.gov/15569249
Autor:
B L, Roth
Publikováno v:
Science's STKE : signal transduction knowledge environment. 2000(45)
Proteins used in signal transduction pathways are commonly found in different cell types and organs. However, specific proteins whose expression is highly restricted are also utilized for allowing discrete responsiveness to signals that are otherwise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ae80735699635fc9cad962ce0b6493f
https://pubmed.ncbi.nlm.nih.gov/11752603
https://pubmed.ncbi.nlm.nih.gov/11752603
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Atypical antipsychotic drugs, which are distinguished from typical antipsychotic drugs by a lower incidence of extra-pyramidal side effects and less propensity to elevate serum prolactin levels (e.g., clozapine, olanzapine, risperidone, quetiapine, z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c57dfb3fadbfb4821d67c04074c74cef
https://pubmed.ncbi.nlm.nih.gov/11561066
https://pubmed.ncbi.nlm.nih.gov/11561066
Publikováno v:
Synapse (New York, N.Y.). 39(4)
Treatment with conventional antipsychotic drugs (APDs) is accompanied by extrapyramidal side effects (EPS), which are thought to be due to striatal dopamine D(2) receptor blockade. In contrast, treatment with atypical APDs is marked by a low incidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8f5732e8f7f341c8dc8734cbe82843c
https://pubmed.ncbi.nlm.nih.gov/11169779
https://pubmed.ncbi.nlm.nih.gov/11169779
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(3)
Discovering the molecular and atomic mechanism(s) by which G-protein-coupled receptors (GPCRs) are activated by agonists remains an elusive goal. Recently, studies examining two representative GPCRs (rhodopsin and alpha(1b)-adrenergic receptors) have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23ed4ef0a4fb41bc52bff86d458aab27
https://pubmed.ncbi.nlm.nih.gov/10869371
https://pubmed.ncbi.nlm.nih.gov/10869371
Autor:
G, Rajkowska, J J, Miguel-Hidalgo, J, Wei, G, Dilley, S D, Pittman, H Y, Meltzer, J C, Overholser, B L, Roth, C A, Stockmeier
Publikováno v:
Biological psychiatry. 45(9)
This report provides histopathological evidence to support prior neuroimaging findings of decreased volume and altered metabolism in the frontal cortex in major depressive disorder.Computer-assisted three-dimensional cell counting was used to reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee9e74419b80cdde26517e2acc1c0d9c
https://pubmed.ncbi.nlm.nih.gov/10331100
https://pubmed.ncbi.nlm.nih.gov/10331100
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fccaa25b7d5ace8081ef49255d9e555b
https://pubmed.ncbi.nlm.nih.gov/9327944
https://pubmed.ncbi.nlm.nih.gov/9327944
Publikováno v:
Synapse (New York, N.Y.). 27(1)
The distribution of 5-HT2A receptors in rat cortex was evaluated using newly developed antibodies. Each of three antibodies tested identified an identical pattern of 5-HT2A-like immunoreactivity (5-HT2A-li) in rat cortex with 5-HT2A-li showing a wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc2c331ec592b251466025e6a315faf3
https://pubmed.ncbi.nlm.nih.gov/9268067
https://pubmed.ncbi.nlm.nih.gov/9268067