Zobrazeno 1 - 10
of 58
pro vyhledávání: '"B L, Hansen"'
Autor:
Ulrik Winning Iepsen, Andreas R. Hjortdal, Anne D. Thuesen, Stine H. Finsen, Pernille B. L. Hansen, Stefan P. Mortensen
Publikováno v:
Experimental Physiology, Vol 109, Iss 5, Pp 779-790 (2024)
Abstract Endothelial dysfunction develops with age and may precede cardiovascular disease. Animal data suggest that T‐type calcium channels play an important role in endothelial function, but data from humans are lacking. This study included 15 hea
Externí odkaz:
https://doaj.org/article/870e04f7bb914426afc02258afe07bc7
Publikováno v:
Physiological Reports, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Aldosterone has been suggested to be involved in the microvascular complications observed in type 2 diabetes. We aimed to investigate the effect of mineralocorticoid receptor (MR) blockade on endothelial function in individuals with type 2 d
Externí odkaz:
https://doaj.org/article/2f8529b21233424398bcd4e0eefe0ef8
Autor:
Alex-Xianghua Zhou, Marie Jeansson, Liqun He, Leif Wigge, Pernilla Tonelius, Ramesh Tati, Linda Cederblad, Lars Muhl, Martin Uhrbom, Jianping Liu, Anna Björnson Granqvist, Lilach O. Lerman, Christer Betsholtz, Pernille B. L. Hansen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4320 (2024)
Endothelial cell (EC) injury is a crucial contributor to the progression of diabetic kidney disease (DKD), but the specific EC populations and mechanisms involved remain elusive. Kidney ECs (n = 5464) were collected at three timepoints from diabetic
Externí odkaz:
https://doaj.org/article/4b92f51ce8dd424b94f406e3b18737c6
Autor:
Ramin Pajoumshariati, Lorna Ewart, Ville Kujala, Raymond Luc, Samantha Peel, Adam Corrigan, Heather Weber, Bramasta Nugraha, Pernille B. L. Hansen, Julie Williams
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract The function of the glomerulus depends on the complex cell–cell/matrix interactions and replication of this in vitro would aid biological understanding in both health and disease. Previous models do not fully reflect all cell types and int
Externí odkaz:
https://doaj.org/article/40d07dfc9c4243bab8676a40760b5937
Autor:
Thore Hillig, Josephine R. Kristensen, Claus L. Brasen, Ivan Brandslund, Dorte A. Olsen, Camilla Davidsen, Jonna S. Madsen, Claus A. Jensen, Young B. L. Hansen, Lennart Friis-Hansen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract To assess if SARS-CoV-2 (COVID-19) systemic disease can be determined by available nucleoprotein assays, we compared the performance of three commercial SARS-CoV-2 nucleoprotein (N) assays in plasma. A total of 272 plasma samples collected i
Externí odkaz:
https://doaj.org/article/00195815aae2461c9c0b3ec6194139e8
Autor:
Alexis Hofherr, Julie Williams, Li-Ming Gan, Magnus Söderberg, Pernille B. L. Hansen, Kevin J. Woollard
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality and morbidity associated with DKD are increasing with the global prevalence of type 2 diabetes. Chronic, sub-clinical, non-resolving inflammation contr
Externí odkaz:
https://doaj.org/article/441494f4155e41ac8b207d9608db287a
Autor:
Lisa Buvall, Robert I. Menzies, Julie Williams, Kevin J. Woollard, Chanchal Kumar, Anna B. Granqvist, Maria Fritsch, Denis Feliers, Anna Reznichenko, Davide Gianni, Slavé Petrovski, Claus Bendtsen, Mohammad Bohlooly-Y, Carolina Haefliger, Regina Fritsche Danielson, Pernille B. L. Hansen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Kidney disease is a complex disease with several different etiologies and underlying associated pathophysiology. This is reflected by the lack of effective treatment therapies in chronic kidney disease (CKD) that stop disease progression. However, no
Externí odkaz:
https://doaj.org/article/6361614ed43a4724915ac1760b7334c8
Autor:
Bartosz Pilecki, Paulo V. S. D. de Carvalho, Katrine L. Kirketerp-Møller, Anders Schlosser, Karin Kejling, Magdalena Dubik, Nicklas P. Madsen, Jane Stubbe, Pernille B. L. Hansen, Thomas L. Andersen, Jesper B. Moeller, Niels Marcussen, Vasco Azevedo, Svend Hvidsten, Christina Baun, Guo-Ping Shi, Jes S. Lindholt, Grith L. Sorensen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objective: Abdominal aortic aneurysm (AAA) is a common age-related vascular disease characterized by progressive weakening and dilatation of the aortic wall. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix (ECM) protein involve
Externí odkaz:
https://doaj.org/article/eb8cd3b728a9421dbd73188ffc0b98f5
Autor:
Henrik Andersen, Maria Høj Hansen, Kristian B. Buhl, Mette Stæhr, Ulla G. Friis, Camilla Enggaard, Shanya Supramaniyam, Ida K. Lund, Per Svenningsen, Pernille B. L. Hansen, Boye L. Jensen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 23 (2020)
Background Diabetic nephropathy is a common diabetes mellitus complication associated with hypertension, proteinuria, and excretion of urinary plasmin that activates the epithelial sodium channel, ENaC, in vitro. Here we hypothesized that the deletio
Externí odkaz:
https://doaj.org/article/89e4a8d381294e9883111bf18a955826
Autor:
Vandana Veenit, Hiddo J L Heerspink, Christine Ahlstrom, Peter J Greasley, Stanko Skritic, Natalie van Zuydam, Donald E Kohan, Pernille B L Hansen, Robert I Menzies
Publikováno v:
Nephrology Dialysis Transplantation.
Background Endothelin A receptor antagonists (ETARA) slow chronic kidney disease (CKD) progression but their use is limited due to fluid retention and associated clinical risks. Sodium glucose cotransporter 2 inhibitors (SGLT2i) cause osmotic diuresi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc177714633d8c65f19be771dac71a4
https://doi.org/10.1093/ndt/gfad078
https://doi.org/10.1093/ndt/gfad078