Zobrazeno 1 - 10
of 30
pro vyhledávání: '"B L, Gallie"'
Autor:
B. L. Gallie, H. Dimaras
Publikováno v:
Retinoblastoma ISBN: 9780387890715
Retinoblastoma was the first cancer to be described as a genetic disease. The progression of a normal retinal cell to the eventual malignant tumor involves a step-wise accumulation of molecular genetic alterations, which correlate with clinical stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3572eacbc64982fa76961b7037a2b1e4
https://doi.org/10.1007/978-0-387-89072-2_4
https://doi.org/10.1007/978-0-387-89072-2_4
Autor:
C, Du, B L, Gallie
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 16(6)
To develop a half-automatic, simple, non-radioactive technique for rapid detection of mutation in the RB gene.Quantitative fluorescent multiplex PCR (QFM-PCR) involves amplification of the promoter region and all 27 exons of the RB1 gene with fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4007e54b7ee83566c76edbab590bc41a
https://pubmed.ncbi.nlm.nih.gov/10581351
https://pubmed.ncbi.nlm.nih.gov/10581351
Autor:
J K, Cowell, B L, Gallie
Publikováno v:
European journal of cancer (Oxford, England : 1990). 34(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f583b18a8f1ca7f782021e04a33483bd
https://pubmed.ncbi.nlm.nih.gov/10023301
https://pubmed.ncbi.nlm.nih.gov/10023301
Autor:
H S, Chan, B L, Gallie, G, DeBoer, G, Haddad, N, Ikegaki, J, Dimitroulakos, H, Yeger, V, Ling
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(10)
About half of nonlocalized neuroblastomas have MYCN gene amplification and usually progress rapidly, but the half without such amplification also do poorly, albeit progressing more slowly. We hypothesize that overexpression of MYCN protein can occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb9a3fea2c403d28510e4e5b6b1ceeb2
https://pubmed.ncbi.nlm.nih.gov/9815553
https://pubmed.ncbi.nlm.nih.gov/9815553
Autor:
H S, Chan, Y, Lu, T M, Grogan, G, Haddad, D R, Hipfner, S P, Cole, R G, Deeley, V, Ling, B L, Gallie
Publikováno v:
Cancer research. 57(12)
Failure of chemotherapy associated with expression of the multidrug resistance protein p170 frequently occurs in retinoblastoma (RB). Despite using cyclosporine, which inhibits p170 and improves our chemotherapy results, rare failures occur. In nonme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::907461b63310cea0000e212e371bfb81
https://pubmed.ncbi.nlm.nih.gov/9192801
https://pubmed.ncbi.nlm.nih.gov/9192801
Publikováno v:
The EMBO journal. 15(21)
The retinoblastoma gene product, pRb, negatively regulates cell proliferation by modulating the activity of the transcription factor E2F1 that controls expression of S-phase genes. To dissect transcriptional regulation of E2F1 by pRb, we developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4eec440b5815ccf10c38c3892a0ba8fa
https://pubmed.ncbi.nlm.nih.gov/8918469
https://pubmed.ncbi.nlm.nih.gov/8918469
Autor:
H S, Chan, G, DeBoer, J J, Thiessen, A, Budning, J E, Kingston, J M, O'Brien, G, Koren, E, Giesbrecht, G, Haddad, Z, Verjee, J L, Hungerford, V, Ling, B L, Gallie
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(9)
Chemotherapy without radiation has not controlled most intraocular retinoblastoma, perhaps because of the common high expression of multidrug resistance P-glycoprotein that we found in retinoblastoma. Cyclosporin blocks P-glycoprotein-induced efflux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5e6f051a72639b317b7a5b8ed0eb12f
https://pubmed.ncbi.nlm.nih.gov/9815710
https://pubmed.ncbi.nlm.nih.gov/9815710
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 5(5)
The retinoblastoma gene (RB1) is a recessive oncogene implicated in a number of human tumors. Although the RB1 gene is expressed in most proliferating cells, there is considerable evidence for the transcriptional regulation of this gene. Therefore, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de7615b6a0bb2e715608f05741c82c77
https://pubmed.ncbi.nlm.nih.gov/8049153
https://pubmed.ncbi.nlm.nih.gov/8049153
Publikováno v:
Oncogene. 9(4)
The class II major histocompatibility (MHC) genes encode cell surface heterodimers that present processed antigen to CD4 positive T-cells. The class II genes are expressed constitutively on B-cells and can be induced by IFN-gamma on a variety of othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2b1e3137c3db2dbaab7c37cc6fd5502
https://pubmed.ncbi.nlm.nih.gov/8134104
https://pubmed.ncbi.nlm.nih.gov/8134104
Publikováno v:
Hematology/oncology clinics of North America. 8(2)
Increased P-glycoprotein expression has been shown to be the molecular cause of multidrug resistance in tumor cell lines. Sensitive immunohistochemical and molecular biologic techniques have been developed to detect P-glycoprotein/mdr1 mRNA expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::578f131ac63ca18fb01c69eed88cfe45
https://pubmed.ncbi.nlm.nih.gov/7913705
https://pubmed.ncbi.nlm.nih.gov/7913705