Výsledky vyhledávání - "B L, Asselin"

The three asparaginases. Comparative pharmacology and optimal use in childhood leukemia

Autor: B L, Asselin

Publikováno v: Advances in experimental medicine and biology. 457

Asparaginase (ASP) is a standard component of the antileukemia armamentarium. There are currently 3 preparations of asparaginase available: (1) E. coli (ASP, Elspar); (2) the enzyme derived from Erwinia chrysanthemi (ERW, Erwinase); (3) pegaspargase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a66f5c9202b8ab1dec36e3214c65288
https://pubmed.ncbi.nlm.nih.gov/10500842

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Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor

Autor: B L, Asselin, M Y, Lorenson, J C, Whitin, D J, Coppola, A S, Kende, R L, Blakley, H J, Cohen

Publikováno v: Cancer research. 51(24)

The antileukemic activity of L-asparaginase (ASNase), an important component of therapy for acute lymphoblastic leukemia, is thought to result from depletion of serum L-asparagine (Asn). In studies of the pharmacological effects of ASNase, investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8aa19a24eabaf3e458a8748d89bd830c
https://pubmed.ncbi.nlm.nih.gov/1742729

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Maternal disease as a consideration in lactation management

Autor: B L, Asselin, R A, Lawrence

Publikováno v: Clinics in perinatology. 14(1)

Breastfeeding for mothers with chronic medical conditions presents important medical decisions for the primary physician. The issues need to be considered in light of the chronic disease, the physiological process of lactation, and the individual Mot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e65c67187bcb9684d2cf9054578d128b
https://pubmed.ncbi.nlm.nih.gov/3549116

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In vitro and in vivo killing of acute lymphoblastic leukemia cells by L-asparaginase

Autor: B L, Asselin, D, Ryan, C N, Frantz, S D, Bernal, P, Leavitt, S E, Sallan, H J, Cohen

Publikováno v: Cancer research. 49(15)

L-Asparaginase (ASNase) is a potent antileukemic enzyme routinely used in the treatment of children with acute lymphoblastic leukemia. As part of investigations of the biological activity of ASNase, we have developed techniques which measure the in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6fcbae8782293a992f85f84f38a77c50
https://pubmed.ncbi.nlm.nih.gov/2743326

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