Zobrazeno 1 - 10
of 23
pro vyhledávání: '"B K, Weir"'
Publikováno v:
Neurosurgery clinics of North America. 9(4)
Middle cerebral artery (MCA) aneurysms account for approximately 20% of aneurysmal subarachnoid hemorrhage (SAH). An understanding of MCA anatomy and variations is the key to successful treatment of MCA aneurysms, which may occur on the M1 segment, a
Publikováno v:
Neurosurgery clinics of North America. 9(3)
Aneurysmal subarachnoid hemorrhage during pregnancy is rare but is an important cause of maternal mortality. Physiologic changes in pregnancy may predispose to aneurysm formation and rupture. In general, neurosurgical considerations take precedence o
Publikováno v:
Surgical neurology. 47(4)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(3)
Erythrocyte components released from blood clot after subarachnoid hemorrhage are thought to be involved in the pathogenesis of cerebral vasospasm. The effect of erythrocyte components on smooth muscle has been investigated extensively; however, thei
Autor:
J M, Findlay, N F, Kassell, B K, Weir, E C, Haley, G, Kongable, T, Germanson, L, Truskowski, W M, Alves, R O, Holness, N W, Knuckey
Publikováno v:
Neurosurgery. 37(1)
A multicenter, randomized, blinded, placebo-controlled trial was conducted to study the possible role of intracisternally administered fibrinolytic agent recombinant tissue plasminogen activator (rt-PA) in preventing delayed onset cerebral vasospasm
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 19(4)
This paper reviews our recent studies on the mechanism of cerebral vasospasm following subarachnoid hemorrhage (SAH) in monkeys. Middle cerebral artery (MCA) vasospasm was maximal at 7 days, resolving by 14 days, and absent at 28 days after SAH. Arte
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 19(3)
Cerebral vasospasm may result from lipid peroxidation induced by oxyhemoglobin in the subarachnoid space after subarachnoid hemorrhage. To test this theory, vasospasm was induced in monkeys by intrathecal injections of oxyhemoglobin or supernatant fl
Autor:
B K, Weir
Publikováno v:
Neuro-Chirurgie. 38(3)
We have studied chronic vasospasm (V.S.) on a primate model (Cynomolgus monkey). The conclusion of several studies are: V.S. is related to the presence of adherent clots along cerebral arteries and when severe may lead to cerebral infarction. Clots r
Publikováno v:
Cancer research. 51(9)
A large-animal model was developed to facilitate the noninvasive investigation of the effect on the human glioma-derived D-54 MG (glioblastoma multiforme) continuous cell line of a variety of therapeutic regimens. Twenty random-bred male cats were in
Publikováno v:
Cerebrovascular and brain metabolism reviews. 3(4)
Approximately 10 in 100,000 persons suffer rupture of a saccular intracranial aneurysm annually, and roughly 60% of these will survive the initial catastrophe in reasonable neurological condition. Of the many ensuing complications of aneurysmal subar