Zobrazeno 1 - 10
of 12
pro vyhledávání: '"B K, Singleton"'
Autor:
R. Mushens, A. Bomford, Momin Ahmed, M. J. Woźniak, C. A. Green, Lepakshi Ranjha, F. Seeney, M.-J. King, A. Guest, B. K. Singleton, P. Mehta, H. Heimpel
Publikováno v:
Cytometry Part B: Clinical Cytometry. 94:312-326
Background: Bone marrow examination has been the confirmatory test for congenital dyserythropoietic anemia type II (CDAII). Occasional spherocytes on peripheral blood smear can confound the diagnosis. Since a screening test is still unavailable, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::407dc5bdb3fa493c012c6a6dcb1f22e8
https://doi.org/10.1002/cyto.b.21488
https://doi.org/10.1002/cyto.b.21488
Autor:
B K, Singleton, M, Ahmed, C A, Green, H, Heimpel, M J, Woźniak, L, Ranjha, F, Seeney, A, Bomford, P, Mehta, A, Guest, R, Mushens, M-J, King
Publikováno v:
Cytometry. Part B, Clinical cytometry. 94(2)
Bone marrow examination has been the confirmatory test for congenital dyserythropoietic anemia type II (CDAII). Occasional spherocytes on peripheral blood smear can confound the diagnosis. Since a screening test is still unavailable, we explored the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f9261b1f9eb6f3bff808ff4d4da9e79
https://pubmed.ncbi.nlm.nih.gov/27784127
https://pubmed.ncbi.nlm.nih.gov/27784127
Autor:
S. T. Rottinghaus, Penny A. Jeggo, Guillermo E. Taccioli, Maria I. Torres-Arzayus, B. K. Singleton
Publikováno v:
Molecular and Cellular Biology. 19:3267-3277
Ku is a heterodimeric protein with double-stranded DNA end-binding activity that operates in the process of nonhomologous end joining. Ku is thought to target the DNA-dependent protein kinase (DNA-PK) complex to the DNA and, when DNA bound, can inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1077e24ee549b77cd175106c06bb28
https://doi.org/10.1128/mcb.19.5.3267
https://doi.org/10.1128/mcb.19.5.3267
Publikováno v:
Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie. 322:109-112
The DNA-dependent protein kinase functions in the repair of DNA double strand breaks (DSBs) and in V(D)J recombination. To gain insight into the function of DNA-PK in this process we have carried out a mutation analysis of Ku80 and DNA-PKcs. Mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac44a143c70526ee23735fabec8deb3
https://doi.org/10.1016/s0764-4469(99)80031-6
https://doi.org/10.1016/s0764-4469(99)80031-6
Autor:
Stephen P. Jackson, P. A. Jeggo, B. K. Singleton, Ethel Moustacchi, Dora Papadopoulo, M Buchwald, Monica Escarceller
Publikováno v:
Journal of Molecular Biology. 279:375-385
Mutations in genes controlling the correct functioning of the replicative, repair and recombination machineries may lead to genomic instability. A high level of spontaneous chromosomal aberrations amplified by treatment with DNA cross-linking agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461576f8be62f98a1c55e592ce07e9d1
https://doi.org/10.1006/jmbi.1998.1784
https://doi.org/10.1006/jmbi.1998.1784
Autor:
B. K. Singleton, Maria C. Muhlmann-Diaz, Tracy Blunt, Graeme C. M. Smith, Stephen P. Jackson, Anne Priestley, P. A. Jeggo, Leonard C. Schalkwyk, Guillermo E. Taccioli, A. G. Amatucci, Joel S. Bedford, David A. Gell, Heather Beamish
Publikováno v:
Nucleic Acids Research. 26:1965-1973
The catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) is a member of a sub-family of phosphatidylinositol (PI) 3-kinases termed PIK-related kinases. A distinguishing feature of this sub-family is the presence of a conserved C-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5900e08c19c3005f4491f00bcdee74e
https://doi.org/10.1093/nar/26.8.1965
https://doi.org/10.1093/nar/26.8.1965
Publikováno v:
Comparative Haematology International. 5:145-148
The Hantronic pneumatic tube system was installed for transporting animal blood specimens from animal accommodation to clinical laboratories for analysis. It provides a safe system that is convenient and effective, and allows for rapid analysis of bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4243ca99906751db3e62d7c9c6b28a
https://doi.org/10.1007/bf00638934
https://doi.org/10.1007/bf00638934
Publikováno v:
Comparative Haematology International. 4:49-54
A haemolysis test has been evaluated as an alternative to the Draize eye test (Draize et al. 1944) for ocular irritancy. Haemolysis was seen with corrosive/ severe and severe/moderate eye irritants but was negligible with non-irritant substances.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f447285424f6db7e3b6253fbe7a087
https://doi.org/10.1007/bf00368267
https://doi.org/10.1007/bf00368267
Autor:
B K, Singleton, C A, Green, N D, Avent, P G, Martin, E, Smart, A, Daka, E G, Narter-Olaga, L M, Hawthorne, G, Daniels
Publikováno v:
Blood. 95(1)
Antigens of the Rh blood group system are encoded by 2 homologous genes, RHD and RHCE, that produce 2 red cell membrane proteins. The D-negative phenotype is considered to result, almost invariably, from homozygosity for a complete deletion of RHD. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8d16ab61fb4f4c379db714ba5408f55
https://pubmed.ncbi.nlm.nih.gov/10607679
https://pubmed.ncbi.nlm.nih.gov/10607679
Autor:
Stephen P. Jackson, H. Steingrimsdottir, Tracy Blunt, David A. Gell, Anne Priestley, B. K. Singleton, Alan R. Lehmann, P. A. Jeggo
Publikováno v:
Europe PubMed Central
The gene product defective in radiosensitive CHO mutants belonging to ionizing radiation complementation group 5, which includes the extensively studied xrs mutants, has recently been identified as Ku80, a subunit of the Ku protein and a component of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b9480f77e542ccf271ca66b2922447
https://pubmed.ncbi.nlm.nih.gov/9032253
https://pubmed.ncbi.nlm.nih.gov/9032253