Zobrazeno 1 - 10
of 14
pro vyhledávání: '"B K, Krueger"'
Publikováno v:
Glia. 19(4)
The regulation of intracellular Ca2+ was investigated in cultured astrocytes from the trisomy 16 (Ts16) mouse, an animal model for Down syndrome and Alzheimer's disease (AD). The cytoplasmic ionized Ca2+ concentration ([Ca2+]cyt) was determined using
Publikováno v:
Journal of neuroscience research. 46(3)
Expression of developmentally regulated antigens was used to characterize glial cells in cultures from embryonic mouse cerebral cortex. Over 90% of the cells had a flat morphology, and about 50% of these flat cells also expressed the ganglioside GD3.
Publikováno v:
Glia. 16(4)
Mechanisms that regulate the amount of releasable Ca2+ in intracellular stores of cultured mouse astrocytes were investigated using digital imaging of fura-2 loaded cells. At rest, the cytoplasmic Ca2+ concentration, [Ca2+]cyt, was about 110 nM. In t
Publikováno v:
The Journal of biological chemistry. 268(25)
We have identified two exons of the type III rat brain sodium channel alpha subunit gene that undergo mutually exclusive alternative RNA splicing to produce mRNAs coding either for an isoform predominant in neonatal brain (IIIN) or a different isofor
Publikováno v:
Molecular pharmacology. 40(6)
Venoms from five Old World and two New World scorpions were tested for their ability to block various K+ channels in rat brain synaptosomes. A 86Rb efflux kinetic assay was used to identify three types of K+ channels, Ca(2+)-independent, voltage-gate
Autor:
B K, Krueger
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 3(8)
The second half of the 1980s is certain to be considered a turning point in the study of ion channels. Within the last few years, monumental advances in the application of molecular biology, single-channel recording, and direct molecular characteriza
Publikováno v:
Psychopharmacology bulletin. 11(4)
Publikováno v:
Molecular pharmacology. 34(2)
Venom from the green mamba (Dendroaspis angusticeps) blocked 86Rb efflux through voltage-gated K channels in rat brain synaptosomes. Crude venom inhibited both rapidly inactivating, 4-aminopyridine-sensitive K channels, and noninactivating, phencycli
Publikováno v:
Molecular pharmacology. 12(4)
Publikováno v:
The Journal of biological chemistry. 252(8)
Agents known to inphorylation of specific endogenous proteins in intact synaptosomes from rat brain. Synaptosome preparations, preincubated in vitro with 32Pi, incorporated 32P into a variety of specific proteins. Veratridine and high (60 mM) K+, whi