Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

Autor: Simon B. K. Jensen, Christian R. Juhl, Charlotte Janus, Julie R. Lundgren, Christoffer Martinussen, Christoffer Wiingaard, Cecilie Knudsen, Ruth Frikke‐Schmidt, Bente M. Stallknecht, Jens J. Holst, Sten Madsbad, Signe S. Torekov

Publikováno v: Jensen, S B K, Juhl, C R, Janus, C, Lundgren, J R, Martinussen, C, Wiingaard, C, Knudsen, C, Frikke-Schmidt, R, Stallknecht, B M, Holst, J J, Madsbad, S & Torekov, S S 2023, ' Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function ', Obesity, vol. 31, no. 4, pp. 977-989 . https://doi.org/10.1002/oby.23715

OBJECTIVE: The aim of this study was to investigate glucose tolerance, glucagon response, and beta cell function during a 1-year maintenance period with either exercise, the glucagon-like peptide-1 receptor agonist liraglutide, or the combination aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d353d74882b15849afb3ff06003464
https://doi.org/10.1002/oby.23715

O-018 Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomised controlled trial

Autor: E Andersen, C R Juhl, E T Kjøller, J R Lundgren, C Janus, M Saupstad, L R Ingerslev, S B K Jensen, J J Holst, B M Stallknecht, S Madsbad, S S Torekov, R Barrès

Publikováno v: Human Reproduction. 37

Study question Does diet-induced weight loss improve semen parameters, and are these possible improvements maintained with sustained weight loss? Summary answer An 8-week low-calorie diet-induced weight loss was associated with improved sperm count,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::623e57a0cde51131768afa843caaaa5c
https://doi.org/10.1093/humrep/deac104.018

Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment:a randomized controlled trial

Autor: Emil Andersen, Christian R Juhl, Emma T Kjøller, Julie R Lundgren, Charlotte Janus, Yasmin Dehestani, Marte Saupstad, Lars R Ingerslev, Olivia M Duun, Simon B K Jensen, Jens J Holst, Bente M Stallknecht, Sten Madsbad, Signe S Torekov, Romain Barrès

Publikováno v: Andersen, E, Juhl, C R, Kjøller, E T, Lundgren, J R, Janus, C, Dehestani, Y, Saupstad, M, Ingerslev, L R, Duun, O M, Jensen, S B K, Holst, J J, Stallknecht, B M, Madsbad, S, Torekov, S S & Barrès, R 2022, ' Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment : a randomized controlled trial ', Human Reproduction, vol. 37, no. 7, pp. 1414–1422 . https://doi.org/10.1093/humrep/deac096

STUDY QUESTION Does diet-induced weight loss improve semen parameters, and are these possible improvements maintained with sustained weight loss? SUMMARY ANSWER An 8-week low-calorie diet-induced weight loss was associated with improved sperm concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0eef71514d6abf7ed23cae393b3286
https://curis.ku.dk/portal/da/publications/sperm-count-is-increased-by-dietinduced-weight-loss-and-maintained-by-exercise-or-glp1-analogue-treatment(8e714f37-9727-44b0-a094-31c99f02e037).html

Effect of age and gender on the pharmacokinetics of ebastine after single and repeated dosing in healthy subjects

Autor: M. S. Gillen, Shashank Rohatagi, C Jan, B Pandit, M Aubeneau, B. K. Jensen, G Rhodes

Publikováno v: International journal of clinical pharmacology and therapeutics. 39(3)

Objectives: Ebastine is a potent and selective H1-receptor antagonist indicated for allergic rhinitis which undergoes extensive first pass metabolism by CYP3A4 to form an active metabolite, carebastine. The purpose of the study was to determine age-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf84f4f2b51cab7e8d77b9bbb7294eb8
https://pubmed.ncbi.nlm.nih.gov/11396753

Pharmacokinetics, pharmacodynamics, and safety of inhaled cyclosporin A (ADI628) after single and repeated administration in healthy male and female subjects and asthmatic patients

Autor: S, Rohatagi, F, Calic, N, Harding, M L, Ozoux, J P, Bouriot, S, Kirkesseli, L, DeLeij, B K, Jensen

Publikováno v: Journal of clinical pharmacology. 40(11)

Severe asthmatics treated with oral/inhaled corticosteroids are at risk of side effects (adrenal suppression). Oral cyclosporin A has been effective in asthma treatment, and nebulized cyclosporin A has been administered for approximately 6 months wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7cd5aba4899437f9be937ab6b0a6e47
https://pubmed.ncbi.nlm.nih.gov/11075307