Výsledky vyhledávání

Characterization of guinea-pig eosinophil phosphodiesterase activity. Assessment of its involvement in regulating superoxide generation

Autor: J E, Souness, C M, Carter, B K, Diocee, G A, Hassall, L J, Wood, N C, Turner

Publikováno v: Biochemical pharmacology. 42(4)

Experiments have been performed to characterize guinea-pig peritoneal eosinophil cyclic nucleotide phosphodiesterase (PDE) activity and establish whether it is involved in regulating superoxide (.O2-) generation. Eosinophils were found to contain a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85399545b0a4e8605d6de0d5365bad5b
https://pubmed.ncbi.nlm.nih.gov/1651083

Zobrazit plný text záznamu

Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells

Autor: B K Diocee, J E Souness, S A Moodie, W Martin

Publikováno v: The Biochemical journal. 266(1)

Two cyclic nucleotide phosphodiesterase (PDE) activities were identified in pig aortic endothelial cells, a cyclic GMP-stimulated PDE and a cyclic AMP PDE. Cyclic GMP-stimulated PDE had Km values of 367 microM for cyclic AMP and 24 microM for cyclic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de5adccda73930e0e39b94cc017024e
https://pubmed.ncbi.nlm.nih.gov/2155604

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání