Zobrazeno 1 - 5
of 5
pro vyhledávání: '"B Joseph, Vu"'
Autor:
Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Y. Anne Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov, J. William Langston, Philip D. Gregory, H. Steve Zhang, J. Timothy Greenamyre, Ole Isacson, Birgitt Schüle
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 381-386 (2014)
Parkinson's disease associated mutations in leucine rich repeat kinase 2 (LRRK2) impair mitochondrial function and increase the vulnerability of induced pluripotent stem cell (iPSC)-derived neural cells from patients to oxidative stress. Since mitoch
Externí odkaz:
https://doaj.org/article/d505d3408a924944819f08f5874cf168
Autor:
Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao
Publikováno v:
Nature Medicine. 25:1131-1142
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3
https://doi.org/10.1038/s41591-019-0478-3
Autor:
Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang
Publikováno v:
Nature medicine. 25(7)
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d3620bad8fe21aa64bd37ef53578561
https://pubmed.ncbi.nlm.nih.gov/31263285
https://pubmed.ncbi.nlm.nih.gov/31263285
Autor:
Philip D. Gregory, Edward J. Rebar, Dirk Hockemeyer, Lauren K. Fong, Xiangdong Meng, Lei Zhang, Vikram Khurana, Richard H. Myers, B. Joseph Vu, Susan Lindquist, Qing Gao, Lawrence I. Golbe, Rudolf Jaenisch, H. Steve Zhang, Fyodor D. Urnov, Frank Soldner, Albert W. Cheng, Josee Laganiere, Dmitry Guschin, Raaji Alagappan
Publikováno v:
Cell. 146:318-331
Summary Patient-specific induced pluripotent stem cells (iPSCs) derived from somatic cells provide a unique tool for the study of human disease, as well as a promising source for cell replacement therapies. One crucial limitation has been the inabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28903e051b95b7215ea5ebd0fb54f544
https://doi.org/10.1016/j.cell.2011.06.019
https://doi.org/10.1016/j.cell.2011.06.019
Autor:
H. Steve Zhang, Josee Laganiere, Philip D. Gregory, B. Joseph Vu, Y. Anne Huang, Sally K. Mak, David Paschon, Birgitt Schüle, J. Timothy Greenamyre, Ramya Sundararajan, Fyodor D. Urnov, Malini Vangipuram, J. William Langston, Laurie H. Sanders, Oliver Cooper, Ole Isacson
Publikováno v:
Neurobiology of Disease, Vol 62, Iss, Pp 381-386 (2014)
Parkinson's disease associated mutations in leucine rich repeat kinase 2 (LRRK2) impair mitochondrial function and increase the vulnerability of induced pluripotent stem cell (iPSC)-derived neural cells from patients to oxidative stress. Since mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54da75b1fafd8e00f22eea6ef429a641
https://europepmc.org/articles/PMC3877733/
https://europepmc.org/articles/PMC3877733/
