Zobrazeno 1 - 10
of 33
pro vyhledávání: '"B J van Lenten"'
Autor:
B J Van Lenten, P S Roheim
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 8, Pp 1187-1195 (1982)
The hyperlipidemia associated with aging was characterized in the rat by comparing the plasma lipid, lipoprotein, and apolipoprotein profiles of adult (12 weeks old) and old (96 weeks old) male rats. Compared with those of the adult rats, the VLDL co
Externí odkaz:
https://doaj.org/article/54dc48c966014abeb462fbf5f9f26122
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 11, Pp 1475-1484 (1983)
The hyperlipoproteinemia observed after ovariectomy in rats was previously shown to be associated with increased concentrations of cholesterol, triglycerides, and apolipoproteins B, E, and C. In the present study, it was shown that increases in low d
Externí odkaz:
https://doaj.org/article/4f4318006a994a318dc0f06dec7d899e
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 9, Pp 1243-1247 (1988)
A modification of the method for monocyte isolation reported by Recalde (1984. J. Immunol. Methods. 69: 71-77) is described. Application of the modified method to 36 consecutive healthy adult donors gave a monocyte purity of 73 +/- 8% monocytes with
Externí odkaz:
https://doaj.org/article/339bfd569c3d47cf9313e144a56b5fa2
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 6, Pp 776-778 (1985)
We describe in this study a reliable method for the breeding of the Watanabe heritable hyperlipidemic (WHHL) rabbit. Placing a male and a female WHHL rabbit in the same cage for the purpose of mating resulted in only two pregnancies out of a total of
Externí odkaz:
https://doaj.org/article/834c477ceaba4d008cbc4e2325e6239b
Publikováno v:
Journal of Clinical Investigation. 99:1906-1916
Transgenic mouse lines carrying several copies of the mouse apo A-IV gene were produced. Lipoprotein composition and function, and aortic lesion development were examined. Apo A-IV levels in the plasma of transgenic mice were elevated threefold compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf620eb8b5de49fca309e4d62e56262a
https://doi.org/10.1172/jci119358
https://doi.org/10.1172/jci119358
Autor:
A D Watson, Judith A. Berliner, Aldon J. Lusis, Mary C. Territo, Peter A. Edwards, B J Van Lenten, Joy S. Frank, Mohamad Navab, Diana M. Shih, A M Fogelman, Linda L. Demer, Susan Hama
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 16:831-842
Recent data support the hypothesis that the fatty streak develops in response to specific phospholipids contained in LDL that become trapped in the artery wall and become oxidized as a result of exposure to the oxidative waste of the artery wall cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912a855d6e492605c469bf7770dd13d2
https://doi.org/10.1161/01.atv.16.7.831
https://doi.org/10.1161/01.atv.16.7.831
Publikováno v:
Journal of Clinical Investigation. 95:2104-2110
Iron promotes cellular damage via its capacity to catalyze hydroxyl radical formation and by peroxidation of unsaturated lipids. The major cellular iron storage depot, ferritin, acts as a critical antioxidant defense by sequestering unbound or "free"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5ea5804a8e45670121f3f3cd247bab
https://doi.org/10.1172/jci117898
https://doi.org/10.1172/jci117898
Publikováno v:
Journal of Clinical Investigation. 91:1225-1230
Addition of leumedin, N-[9H-(2,7-dimethylfluorenyl-9-methoxy) carbon]-L-leucine at 30-60 microM together with LDL almost completely prevented the induction of monocyte chemotactic protein mRNA, reduced monocyte chemotactic protein 1 levels by 84%, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ad461cf3d4a30577c7c378314bdb8f
https://doi.org/10.1172/jci116284
https://doi.org/10.1172/jci116284
Autor:
B J van Lenten, A M Fogelman
Publikováno v:
The Journal of Immunology. 148:112-116
The exposure of mononuclear cells to LPS results in a variety of cellular alterations including changes in the expression of various membrane receptors. In human monocyte-macrophages the development of the scavenger receptor, which mediates the uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3866bd6bfaab8389ec8a6a8fc01154ab
https://doi.org/10.4049/jimmunol.148.1.112
https://doi.org/10.4049/jimmunol.148.1.112
Autor:
Tripathi B. Rajavashisth, L. A. Ross, G P Hough, Feng Liao, Aldon J. Lusis, B J Van Lenten, A M Fogelman, Davis C. Drinkwater, Hillel Laks, M Navab
Publikováno v:
Journal of Clinical Investigation. 87:1763-1772
Medium from cocultures of human aortic endothelial cells (HAEC) and smooth muscle cells (HASMC) taken from the same donor contained approximately two- to fourfold more macrophage colony-stimulating factor, granulocyte/macrophage colony-stimulating fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dae029eb17aa9aba96516e91d73d57
https://doi.org/10.1172/jci115195
https://doi.org/10.1172/jci115195