Zobrazeno 1 - 10
of 11
pro vyhledávání: '"B J, Iacopetta"'
Autor:
R J, Cohen, J E, McNeal, M, Susman, L N, Sellner, B J, Iacopetta, S L, Weinstein, H J, Dawkins
Publikováno v:
Archives of pathologylaboratory medicine. 124(12)
Sarcomatoid renal cell carcinoma (SRCC) is an aggressive tumor variant thought to arise predominantly from dedifferentiation of clear cell carcinoma. A few reports of SRCC associated with non-clear cell tumors led to the presumption that SRCC may ari
Publikováno v:
The Journal of pathology. 187(4)
The replication error phenotype (RER+) represents an important new form of genetic alteration characterized by widespread instability in repetitive nucleotide sequences. The aim of this study was to compare the features of RER+ gastric tumours with t
Publikováno v:
The Journal of pathology. 184(4)
The presence of inactivating mutations in the transforming growth factor-beta (TGF-beta) type II receptor (RII) gene in the colon cancer suggests that it may behave like a tumour suppressor gene. RII is mutated in the majority of colon tumours exhibi
Publikováno v:
International journal of cancer. 74(6)
We examined the association between mutation of the p53 gene and survival in a large cohort of breast cancer patients. Using a rapid, non-isotopic single-strand conformation polymorphism (SSCP) method we screened for mutations in exons 4-10 of the p5
Autor:
R, Soong, B J, Iacopetta
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 10(3)
Evaluation of the clinical significance of p53 gene mutations requires molecular analysis of primary tumors from large series of patients with long follow-up periods. In this study, we describe a sensitive, rapid, nonisotopic and inexpensive procedur
Publikováno v:
Anticancer research. 17(1A)
Abnormal methylation of DNA is one of the earliest detectable changes in human tumors. We investigated hypermethylation of the Myf-3 gene, the human homolog of the mouse myogenic gene Myo-D1, in colorectal adenomas and adenocarcinomas. Histologically
Publikováno v:
International journal of cancer. 69(3)
The aim of our study was to examine the prognostic significance of p53 protein accumulation and gene mutation in a series of 116 gastric carcinomas from a low incidence population. Formalin-fixed, paraffin-embedded tumour sections were used to invest
An electron-microscope autoradiographic study of transferrin endocytosis by immature erythroid cells
Autor:
B J, Iacopetta, E H, Morgan
Publikováno v:
European journal of cell biology. 32(1)
The receptor-mediated endocytosis of 125I-transferrin by immature erythroid cells was studied using the technique of quantitative electron microscope autoradiography. Morphometric analysis of the grain distribution in erythroid cells from the foetal
Autor:
B J, Iacopetta, E H, Morgan
Publikováno v:
Biomedica biochimica acta. 42(11-12)
Electron microscope autoradiography was used to quantitate the uptake of transferrin and transferrin-bound iron by rat erythroid cells at the various stages of development. The capacity of the cells to take up iron closely paralleled their ability to
Autor:
B J, Iacopetta, E H, Morgan
Publikováno v:
The Journal of biological chemistry. 258(15)
The endocytosis of diferric transferrin and accumulation of its iron by freshly isolated rabbit reticulocytes was studied using 59Fe-125I-transferrin. Internalized transferrin was distinguished from surface-bound transferrin by its resistance to rele