Zobrazeno 1 - 2
of 2
pro vyhledávání: '"B J, Haertlein"'
Autor:
P, Andrade-Gordon, C K, Derian, B E, Maryanoff, H C, Zhang, M F, Addo, Cheung Wm, B P, Damiano, M R, D'Andrea, A L, Darrow, L, de Garavilla, A J, Eckardt, E C, Giardino, B J, Haertlein, D F, McComsey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(1)
Human platelets possess two distinct thrombin-activated receptors, PAR-1 (protease-activated receptor-1) and PAR-4, whereas human vascular smooth muscle cells possess only PAR-1. Although such thrombin receptors have been studied extensively in vitro
Publikováno v:
Journal of cardiovascular pharmacology. 23(2)
RWJ-29009, (6S)-trans(-)-1-(6,7-dihydro-6-hydroxy-5,5-dimethyl-2-nitro-5 H-thieno[3,2-b]pyran-7-yl)-2-piperidinone, is a structurally novel and extremely potent potassium channel activator that may be useful for treatment of hypertension and ischemic