Výsledky vyhledávání - "B J, Bolognese"

Modulation of human monocyte activities by tranilast, SB 252218, a compound demonstrating efficacy in restenosis

Autor: E A, Capper, A K, Roshak, B J, Bolognese, P L, Podolin, T, Smith, D L, Dewitt, K M, Anderson, L A, Marshall

Publikováno v: The Journal of pharmacology and experimental therapeutics. 295(3)

Tranilast (SB 252218) is a compound initially identified as an anti-atopic agent. Recently the compound has demonstrated clear beneficial effects in animal models of restenosis. Here we confirm tranilast has broad and profound effects on human monocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af83dac0c4339c600f89f907a46076b0
https://pubmed.ncbi.nlm.nih.gov/11082441

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Inhibition of CD23 processing correlates with inhibition of IL-4-stimulated IgE production in human PBL and hu-PBL-reconstituted SCID mice

Autor: R J, Mayer, B J, Bolognese, N, Al-Mahdi, R M, Cook, P L, Flamberg, M J, Hansbury, S, Khandekar, E, Appelbaum, A, Faller, L A, Marshall

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 30(5)

CD23, the low affinity serum immunoglobulin E (IgE) receptor, is upregulated on B cells following interleukin (IL)-4 stimulation and is concomitantly cleaved to generate soluble CD23 (sCD23) fragments with cytokine-like activity.Compounds that select

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db7dd15c1b06c28feb3ba03e9a3c14b5
https://pubmed.ncbi.nlm.nih.gov/10792350

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Inhibitors of the p38 mitogen-activated kinase modulate IL-4 induction of low affinity IgE receptor (CD23) in human monocytes

Autor: L A, Marshall, M J, Hansbury, B J, Bolognese, R J, Gum, P R, Young, R J, Mayer

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(11)

CD23, the low affinity IgE receptor, is up-regulated on the surface of IL-4-treated B cells and monocytes and is immediately proteolytically processed, releasing soluble fragments of CD23. Here, we report that inhibitors of the p38 mitogen-activated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c4fb5c4faf3bf38076d80f9704131ef
https://pubmed.ncbi.nlm.nih.gov/9834082

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Quantitation of human tissue and immune cell type II 14 kDa phospholipase A(2) by enzyme immunoassay

Autor: L. A. Marshall, S. D. Holmes, L. J. McMillan, K. F. Kaiser, B. J. Bolognese

Publikováno v: Inflammopharmacology. 5(3)

The metabolism of arachidonic acid into inflammatory mediators (e.g. prostaglandin, leukotrienes) is dependent upon the rate-limiting enzyme phospholipase A(2). Localization and quantification of type II 14 kDa phospholipase A(2) (PLA(2)) in cells or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e91d76cbd74d54cdd7c3805076b15b6
https://pubmed.ncbi.nlm.nih.gov/17638134

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