Zobrazeno 1 - 10
of 59
pro vyhledávání: '"B J, Abbott"'
Autor:
Maria Ines Nicoletti, Gabriella Massazza, Raffaella Giavazzi, B. J. Abbott, Valeria Lucchini, Maurizio D'Incalci
Publikováno v:
Europe PubMed Central
Summary Background The unique mechanism of action of taxol (NSC-125973) as microtubule stabilizing agent and its potential activity in clinical trials have generated considerable interest in the development of this agent. As taxol was reported to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9598a792bd0fb43e21b7fca4bcf9e0f7
https://doi.org/10.1093/oxfordjournals.annonc.a058419
https://doi.org/10.1093/oxfordjournals.annonc.a058419
Publikováno v:
Cancer research. 55(4)
Quinocarmycin monicitrate (KW2152) and its analogue, DX-52-1, demonstrated specificity for melanomas in the National Cancer Institute in vitro human tumor cell line drug screen. In contrast to most cell lines, a 50% reduction in tumor cell burden (as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc6af2685d1c94f1806b121a08811f14
https://pubmed.ncbi.nlm.nih.gov/7850800
https://pubmed.ncbi.nlm.nih.gov/7850800
Autor:
Richard F. Camalier, Michael C. Alley, B. J. Abbott, Louis Malspeis, Melinda G. Hollingshead, Michael R. Grever, Joseph G. Mayo
Publikováno v:
Life sciences. 57(2)
Advancement of potential anti-cancer agents from "discovery" in an in vitro screen to pre-clinical development requires a demonstration of in vivo efficacy in one or more animal models of neoplastic disease. Most such models require considerable mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0182b9b9b4c6534cf595fd7696317dd9
https://pubmed.ncbi.nlm.nih.gov/7603295
https://pubmed.ncbi.nlm.nih.gov/7603295
Autor:
R H, Shoemaker, D J, Dykes, J, Plowman, S D, Harrison, D P, Griswold, B J, Abbott, J G, Mayo, O, Fodstad, M R, Boyd
Publikováno v:
Cancer research. 51(11)
In vivo studies aimed at therapy of spontaneous human tumor metastases have been hampered by the lack of practical experimental models. The LOX amelanotic melanoma model described here represents a transplantation model which rapidly and reproducibly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c2821aab151299e0530c1d513e94b49
https://pubmed.ncbi.nlm.nih.gov/2032224
https://pubmed.ncbi.nlm.nih.gov/2032224
Autor:
B. J. Abbott, Joseph G. Mayo, Mary Gregg, Walter C. Hubbard, Robert H. Shoemaker, Theodore L. McLemore, Michael R. Boyd, Michael C. Alley, Charles L. Litterst, Joseph C. Eggleston, Susan E. Jessee, Robert H. Brennan, Penny C. Blacker, Donald L. Fine
Publikováno v:
Chest. 91:5s-8s
5S ond study consisted of 70 golden syrian hamsters: 54 experimental and 16 control animals. The implantation of the thread in the trachea induced a regenerative basal cell hyperplasia of the epithelium. We Ibund squamous metaplasia and progressive i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0472fadea4dc990b26dffaaf998e90b9
https://doi.org/10.1378/chest.91.3_supplement.5s
https://doi.org/10.1378/chest.91.3_supplement.5s
Autor:
Leonard C. Howard, R. M. Molloy, T. F. Butler, M. Barnhart, B. J. Abbott, A. S. Hunt, K. E. Willard, D. S. Fukuda, J. R. Turner, Robert S. Gordee, Doug Zeckner, Manuel Debono
Publikováno v:
Annals of the New York Academy of Sciences. 544:152-167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a73073112bc660806963a3b07459b4
https://doi.org/10.1111/j.1749-6632.1988.tb40398.x
https://doi.org/10.1111/j.1749-6632.1988.tb40398.x
Autor:
B. J. Abbott
Publikováno v:
Journal of General Microbiology. 75:383-389
SUMMARY: Acinetobacter calcoaceticus, a soil isolate capable of utilizing ethanol as a sole carbon source, was cultivated in a chemostat under ethanol-limiting conditions. The pulse addition of ethanol (to less than 0.1% final concentration) to stead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cfc0404be0dc0ad5d6329ebb243d2f9
https://doi.org/10.1099/00221287-75-2-383
https://doi.org/10.1099/00221287-75-2-383
Publikováno v:
Experientia. 33:718-720
Microorganisms were screened for their ability to modify 2 synthetic cannabinoid substrates (I and II). Structure analyses revealed that microorganisms transformed the substrates by (a) primary oxidation of the side chain, beta-oxidation of the side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bee5c4226e42609c02b7e1666a7d07
https://doi.org/10.1007/bf01944147
https://doi.org/10.1007/bf01944147
Publikováno v:
Applied and environmental microbiology. 37(5)
A screening program was conducted to find microorganisms that modify the synthetic cannabinoid nabilone. After purification, the products from three cultures were analyzed by spectral methods to determine their chemical structures. An optically activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be733cb5da83bd0de880a375b12075c
https://pubmed.ncbi.nlm.nih.gov/114111
https://pubmed.ncbi.nlm.nih.gov/114111