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pro vyhledávání: '"B H, Mathison"'
Autor:
Scott P, Henry, D K, Monteith, J E, Matson, B H, Mathison, K S, Loveday, R A, Winegar, P S, Lee, E S, Riccio, J P, Bakke, A A, Levin
Publikováno v:
Mutagenesis. 17(3)
ISIS 2302, a phosphorothioate oligodeoxynucleotide with antisense activity against human ICAM-1 mRNA, was evaluated in a battery of tests to assess genotoxic potential. There was no evidence of genotoxicity in three in vitro studies performed: (i) a
Publikováno v:
Mutation research. 380(1-2)
Anatomical, physiological, biochemical and molecular factors that contribute to chemical-induced nasal carcinogenesis are either largely divergent between test species and humans, or we know very little of them. These factors, let alone the uncertain