Zobrazeno 1 - 10
of 20
pro vyhledávání: '"B H, Koller"'
Publikováno v:
The Journal of Immunology. 159:4376-4381
The MRL/MpJ-Fas(lpr) (MRL-lpr/lpr) mouse spontaneously develops a generalized autoimmune disease with features similar to those of systemic lupus erythematosus. This mouse strain provides a valuable system for identifying and characterizing the multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061fbf0b22be16aa6f61048c860c97fb
https://doi.org/10.4049/jimmunol.159.9.4376
https://doi.org/10.4049/jimmunol.159.9.4376
Publikováno v:
The Journal of Immunology. 149:1947-1956
The HLA class I gene family in lymphoblastoid cell line 721 has been studied in detail and a number of sequences in addition to the classical genes have been identified. The cloning, characterization, and nucleotide sequences of four sequences, all f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9eb6f30856b0ae030c47edba998eb3f
https://doi.org/10.4049/jimmunol.149.6.1947
https://doi.org/10.4049/jimmunol.149.6.1947
Publikováno v:
The Journal of clinical investigation. 108(8)
Production of prostaglandin E(2) (PGE(2)) is enhanced during inflammation, and this lipid mediator can dramatically modulate immune responses. There are four receptors for PGE(2) (EP1-EP4) with unique patterns of expression and different coupling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c73bb675f8cd1b2dd85505405d110c9
https://pubmed.ncbi.nlm.nih.gov/11602631
https://pubmed.ncbi.nlm.nih.gov/11602631
Publikováno v:
Cancer research. 61(17)
Loss of p53 function is known to compromise cell cycle regulation, inductionof apoptosis, and DNA damage repair and can facilitate neoplastic transformation of cells. Mutations in the p53 gene are identified frequently in breast carcinomas. Li-Fraume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79021782ed6e4a394808ad6137b92b4d
https://pubmed.ncbi.nlm.nih.gov/11522657
https://pubmed.ncbi.nlm.nih.gov/11522657
Autor:
L M, Bennett, K A, McAllister, J, Malphurs, T, Ward, N K, Collins, J C, Seely, L C, Gowen, B H, Koller, B J, Davis, R W, Wiseman
Publikováno v:
Cancer research. 60(13)
Women who inherit mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, are predisposed to the development of breast and ovarian cancer. We used mice with a Brca1 mutation on a BALB/cJ inbred background (BALB/cB1+/- mice) or a Brca2 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::905929b82f2198e61cc2147dc974e9d8
https://pubmed.ncbi.nlm.nih.gov/10910057
https://pubmed.ncbi.nlm.nih.gov/10910057
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(12)
Arachidonic acid metabolism by 5-lipoxygenase leads to production of the potent inflammatory mediators, leukotriene (LT) B4 and the cysteinyl LT. Relative synthesis of these subclasses of LT, each with different proinflammatory properties, depends on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8a96e545cd869cc27b80a59c6a06627
https://pubmed.ncbi.nlm.nih.gov/10586081
https://pubmed.ncbi.nlm.nih.gov/10586081
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(1)
Leukotrienes, the 5-lipoxygenase (5LO) products of arachidonic acid metabolism, have many proinflammatory actions that have been implicated in the pathogenesis of a variety of inflammatory diseases. To investigate the role of LTs in autoimmune diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b7a56783103c72df38a676f4ac86004
https://pubmed.ncbi.nlm.nih.gov/10384136
https://pubmed.ncbi.nlm.nih.gov/10384136
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(6)
The regulation of monocyte function and the inhibition of TNF-alpha production during bacterial sepsis are critical in attenuating adverse host responses to endotoxemia. To study the function of a novel receptor tyrosine kinase, mer, that is expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c9ba6be446a4cae4b74ae84b9a2c705
https://pubmed.ncbi.nlm.nih.gov/10092806
https://pubmed.ncbi.nlm.nih.gov/10092806
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 10(1)
The inheritance of a mutant copy of the BRCA1 gene greatly increases a woman's lifetime risk for ovarian and breast cancer. While a homologous gene has been identified in mouse, mice carrying mutations in this gene do not display a detectable increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d09a59590d93e34b500a7b7d7749531
https://pubmed.ncbi.nlm.nih.gov/9950212
https://pubmed.ncbi.nlm.nih.gov/9950212
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(9)
The MRL/MpJ-Fas(lpr) (MRL-lpr/lpr) mouse spontaneously develops a generalized autoimmune disease with features similar to those of systemic lupus erythematosus. This mouse strain provides a valuable system for identifying and characterizing the multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2dd7d948e71868dddd457cc48c8c47b
https://pubmed.ncbi.nlm.nih.gov/9379035
https://pubmed.ncbi.nlm.nih.gov/9379035