Neutralizing Host Responses in Hepatitis C Virus Infection Target Viral Entry at Postbinding Steps and Membrane Fusion

Autor: George Koutsoudakis, Françoise Stoll-Keller, Michel Doffoel, Marlène Dreux, François-Loïc Cosset, E.K. Schnober, Erik Depla, B. Gissler, Thomas F. Baumert, P. Carolla, Hubert E. Blum, Mirjam B. Zeisel, A. Haberstroh, Ralf Bartenschlager, Catherine Schuster, Arvind H. Patel, Anna M. Owsianka, Heidi Barth

Publikováno v: Gastroenterology
Gastroenterology, WB Saunders, 2008, 135 (5), pp.1719-1728.e1. ⟨10.1053/j.gastro.2008.07.018⟩
Gastroenterology, 2008, 135 (5), pp.1719-1728.e1. ⟨10.1053/j.gastro.2008.07.018⟩

Hepatitis C virus (HCV) is a leading cause of chronic hepatitis worldwide. Viral attachment and entry, representing the first steps of virus-host cell interactions, are major targets of adaptive host cell defenses. The mechanisms of antibody-mediated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84aa91826486069b724084f1c5b9b905
https://hal.archives-ouvertes.fr/hal-03295883

Host cell responses induced by hepatitis C virus binding

Autor: Gerd Walz, Marcel Geyer, Johannes Donauer, Jens Timmer, Robert Thimme, Hubert E. Blum, Thomas Baumert, Clemens Kreutz, Erik Depla, Mirjam B. Zeisel, Thomas Maiwald, Fritz von Weizsäcker, Jochen Wilpert, Winfried V. Kern, Xinhua Fang, B. Gissler

Publikováno v: Hepatology (Baltimore, Md.). 43(6)

Initiation of hepatitis C virus (HCV) infection is mediated by docking of the viral envelope to the hepatocyte cell surface membrane followed by entry of the virus into the host cell. Aiming to elucidate the impact of this interaction on host cell bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec1cff521d428db1b29ffe8eec9b825
https://pubmed.ncbi.nlm.nih.gov/16729312

Scavenger Receptor Class B Type I and Hepatitis C Virus Infection of Primary Tupaia Hepatocytes

Autor: Marco Hoffmann, Mirko Arcuri, Thomas Baumert, Alessandra Vitelli, Valeria Ghisetti, B. Gissler, Peter Schürmann, Raffaele Cerino, Hubert E. Blum, Heidi Barth, Fritz von Weizsäcker, Elisa Scarselli, Xiping Zhao, Mohammed I. Adah, Bruna Lavezzo

Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. The study of early steps during HCV infection has been hampered by the lack of suitable in vitro or in vivo models. Primary Tupaia hepatocytes (PTH) have been shown to be suscep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74dd9b5a1a7ad5887293f68d1d6d42e
https://europepmc.org/articles/PMC1082724/

Hepatitis C Virus Structural Proteins and Activation of Toll-Like Receptors

Autor: B. Gissler, M. Hoffmann, P. Henneke, G. Paranhos-Baccalà, Hubert E. Blum, D. T. Golenbock, Thomas Baumert, Heidi Barth

Publikováno v: Zeitschrift für Gastroenterologie. 43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7f91093dc9de6f161aedea72901fdf8
https://doi.org/10.1055/s-2005-862294

Binding of Hepatitis C Virus Envelope to Target Cells Induces a Cascade of Cell Signals Important for Antiviral Immune Responses and Lipid Metabolism

Autor: Clemens Kreutz, Heidi Barth, F. von Weizsäcker, B. Gissler, X. Fang, Johannes Donauer, Hubert E. Blum, Thomas Baumert, Jochen Wilpert

Publikováno v: Zeitschrift für Gastroenterologie. 42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::649d1c2db87570881a848e8241403d44
https://doi.org/10.1055/s-2004-816161