Zobrazeno 1 - 10
of 81
pro vyhledávání: '"B Falgout"'
Publikováno v:
Journal of Virology. 67:2034-2042
Most proteolytic cleavages in the nonstructural protein (NS) region of the flavivirus polyprotein are effected by a virus-encoded protease composed of two viral proteins, NS2B and NS3. The N-terminal 180-amino-acid-region of NS3 includes sequences wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f44cc524153a26f16ed2d2d651daa55
https://doi.org/10.1128/jvi.67.4.2034-2042.1993
https://doi.org/10.1128/jvi.67.4.2034-2042.1993
Publikováno v:
Journal of Virology. 66:7225-7231
We have previously shown that proper processing of dengue type 4 virus NS1 from the NS1-NS2A region of the viral polyprotein requires a hydrophobic N-terminal signal and the downstream NS2A. Results from deletion analysis indicate that a minimum leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6444c7f4359d451b582d69c5a21c70
https://doi.org/10.1128/jvi.66.12.7225-7231.1992
https://doi.org/10.1128/jvi.66.12.7225-7231.1992
Publikováno v:
Journal of Virology. 65:2467-2475
The cleavages at the junctions of the flavivirus nonstructural (NS) proteins NS2A/NS2B, NS2B/NS3, NS3/NS4A, and NS4B/NS5 share an amino acid sequence motif and are presumably catalyzed by a virus-encoded protease. We constructed recombinant vaccinia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cedf7a102977b7d9348dee552e9ee912
https://doi.org/10.1128/jvi.65.5.2467-2475.1991
https://doi.org/10.1128/jvi.65.5.2467-2475.1991
Autor:
Vannakambadi K. Ganesh, Radhakrishnan Padmanabhan, Sukathida Ubol, Nagarajan Pattabiraman, Ratree Takhampunya, Changsuek Yon, E Reichert, Y Kono, B Falgout, Tadahisa Teramoto, Krishna H. M. Murthy, Niklaus H. Mueller
Publikováno v:
New Treatment Strategies for Dengue and Other Flaviviral Diseases: Novartis Foundation Symposium 277
Dengue viruses (DENV) have 5'-capped RNA genomes of (+) polarity and encode a single polyprotein precursor that is processed into mature viral proteins. NS2B, NS3 and NS5 proteins catalyse/activate enzyme activities that are required for key processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9e938b1a7f426881c9a3bae118dfef5
https://doi.org/10.1002/0470058005.ch6
https://doi.org/10.1002/0470058005.ch6
Publikováno v:
Journal of Virology. 64:4356-4363
The protective immunity conferred by a set of recombinant vaccinia viruses containing the entire coding sequence of dengue virus type 4 nonstructural glycoprotein NS1 plus various flanking sequences was evaluated by using a mouse encephalitis model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b72e1583053eee31965b21a73631c4
https://doi.org/10.1128/jvi.64.9.4356-4363.1990
https://doi.org/10.1128/jvi.64.9.4356-4363.1990
Autor:
R, Padmanabhan, N, Mueller, E, Reichert, C, Yon, T, Teramoto, Y, Kono, R, Takhampunya, S, Ubol, N, Pattabiraman, B, Falgout, V K, Ganesh, K, Murthy
Publikováno v:
Novartis Foundation symposium. 277
Dengue viruses (DENV) have 5'-capped RNA genomes of (+) polarity and encode a single polyprotein precursor that is processed into mature viral proteins. NS2B, NS3 and NS5 proteins catalyse/activate enzyme activities that are required for key processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0f2a3c8e4c67407273bcbb9019c146b
https://pubmed.ncbi.nlm.nih.gov/17319155
https://pubmed.ncbi.nlm.nih.gov/17319155
Publikováno v:
Virus genes. 20(1)
The flavivirus dengue 1 Western Pacific,74 (DEN1 WP) virus has a positive-stranded RNA genome of 10,735 nucleotides. DEN1 WP genomic RNA was amplified into three overlapping fragments by RT-PCR. These fragments were assembled into a full-length cDNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::035f238295898e0cf907a05a21bf9921
https://pubmed.ncbi.nlm.nih.gov/10766307
https://pubmed.ncbi.nlm.nih.gov/10766307
Publikováno v:
Journal of virology. 69(11)
Previous deletion mutagenesis studies have shown that the flavivirus NS1-NS2A clevage requires the eight C-terminal residues of NS1, constituting the cleavage recognition sequence, and sequences in NS2A far downstream of the cleavage site. We now dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5997dc699052d60196f14b2db5cdc753
https://pubmed.ncbi.nlm.nih.gov/7474145
https://pubmed.ncbi.nlm.nih.gov/7474145
Publikováno v:
Positive-Strand RNA Viruses ISBN: 9783211825228
Dengue type 4 (DEN4) and other flaviviruses employ host and viral proteases for polyprotein processing. Most proteolytic cleavages in the DEN4 nonstructural protein (NS) region are mediated by the viral NS2B-NS3 protease. The N-terminal third of NS3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::286f37c60772ff6e070a9dca782ebbc2
https://doi.org/10.1007/978-3-7091-9326-6_36
https://doi.org/10.1007/978-3-7091-9326-6_36
Publikováno v:
Archives of virology. Supplementum. 9
Dengue type 4 (DEN4) and other flaviviruses employ host and viral proteases for polyprotein processing. Most proteolytic cleavages in the DEN4 nonstructural protein (NS) region are mediated by the viral NS2B-NS3 protease. The N-terminal third of NS3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d83c7732c6df85f19f4b3a3d1a4a140d
https://pubmed.ncbi.nlm.nih.gov/8032267
https://pubmed.ncbi.nlm.nih.gov/8032267