Zobrazeno 1 - 10
of 36
pro vyhledávání: '"B F Rusy"'
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 31
Publikováno v:
The American journal of physiology. 264(5 Pt 2)
To investigate mechanisms underlying the contractile dysfunction during myocardial "stunning," potentiated contractions were studied in Langendorff-perfused rabbit hearts paced at 2.5 Hz. Isovolumetric left ventricular pressure (LVP) and the first de
Publikováno v:
Advances in experimental medicine and biology. 301
The results of these studies suggest that halothane, in addition to its effect of reducing the trans-sarcolemmal Ca2+ influx, has a direct effect on the function of the sarcoplasmic reticulum by making the organelle leaky to Ca2+ and reducing the amo
Publikováno v:
Anesthesiology. 73
Publikováno v:
Anesthesia and analgesia. 61(5)
The effect of halothane on the availability of different sources of activator calcium for myocardial contraction was evaluated in relationship to the negative inotropic effect on the anesthetic. This was studied in rabbit papillary muscle under vario
Publikováno v:
Anesthesiology. 67(5)
The bulk of experimental evidence indicates that anesthetics do not produce their negative inotropic effect via an inhibitory action on mitochondrial electron transport. Anesthetics decrease energy need, rather than energy production. Anesthetics als
Publikováno v:
Anesthesia and analgesia. 63(3)
The negative inotropic effects of thiopental (10-30 mg/L) and halothane (0.5-1.5%) were compared in rabbit papillary muscles under various stimulation conditions to gain insight into the action of these anesthetics on the availability of Ca2+ for the
Publikováno v:
Anesthesia and analgesia. 66(1)
The possibility that the negative inotropic effect of isoflurane is primarily due to a competitive inhibition of the influx of extracellular Ca2+ with little effect on the availability of Ca2+ stored intracellularly in the sarcoplasmic reticulum was
Autor:
B F, Rusy
Publikováno v:
Anesthesiology. 69(4)
Publikováno v:
Anesthesiology. 55(3)
The intrinsic cardiotoxicities of bupivacaine and lidocaine were examined in the isolated, perfused rat heart. The perfusates contained no protein and were equilibrated with a gas mixture of 95 per cent O2 and 5 per cent CO2. Autonomic activity, comp