Zobrazeno 1 - 10 of 539 pro vyhledávání: '"B Emmerich"'
5
Abstract 4861: Copanlisib enhances the effectiveness of anti-PD1 therapies for colorectal cancer
Autor: Alexa E. Schmitz, Kennedy J. Maduscha, Sarbjeet Makkar, Cheri A. Pasch, Rebecca A. DeStefanis, Philip B. Emmerich, Dustin A. Deming
Publikováno v: Cancer Research. 83:4861-4861
Introduction: Immunotherapies are increasingly being used for patients diagnosed with cancer, however, for metastatic colorectal cancer (CRC), more than 95% of patients have shown little to no clinical benefit to immunotherapy. Previous work from our
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c896f85e0f2bfe54f87174e264c144
https://doi.org/10.1158/1538-7445.am2023-4861
Zobrazit plný text záznamu
6
Novel Murine Pancreatic Tumor Model Demonstrates Immunotherapeutic Control of Tumor Progression by a Toxoplasma gondii Protein
Autor: Laura J. Knoll, Nicole M. Davis, Philip B. Emmerich, Dustin A. Deming, Susan N. Payne
Publikováno v: Infect Immun
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer-related death in the United States, with few effective treatments available and only 10% of those diagnosed surviving 5 years. Although immunotherapeutics is a growing field of st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5257e278826dba9e1c06a26565730f
https://doi.org/10.1128/iai.00508-21
Zobrazit plný text záznamu
8
Abstract 3198: Validation and analysis of cancer associated fibroblast subtype markers in metastatic colorectal cancer
Autor: Anna L. Lippert, Katherine A. Johnson, Cheri A. Pasch, Sean G. Kraus, Philip B. Emmerich, Linda Clipson, Kristina A. Matkowskyj, Wei Zhang, Dustin A. Deming
Publikováno v: Cancer Research. 82:3198-3198
Background: Cancer Associated Fibroblasts (CAFs) are a significant component of tumor stroma, and have an important impact on immune infiltration in the tumor microenvironment (TME). Two major subtypes of CAFs have been previously identified by liter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::703dd71a678cc65436125c41abec599f
https://doi.org/10.1158/1538-7445.am2022-3198
Zobrazit plný text záznamu
9
Abstract 3842: Versican proteolysis is a predictive biomarker of tumor infiltrating lymphocytes within primary and metastatic colorectal cancer tumors
Autor: Sean G. Kraus, Kristina A. Matkowskyj, Philip B. Emmerich, Wei Zhang, Linda Clipson, Cheri A. Pasch, Dustin A. Deming
Publikováno v: Cancer Research. 82:3842-3842
Background: A major roadblock to immune-therapy response in many solid malignancies is the lack of tumor-infiltrating lymphocytes (TILs) found within their immune micro-environments. These immunologically cold tumors have lower response rates to immu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5e56872490f2cb2da7b4562749c7893
https://doi.org/10.1158/1538-7445.am2022-3842
Zobrazit plný text záznamu
10
Abstract 3533: Effects of tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib on cancer-associated fibroblast phenotypes in colorectal cancer
Autor: Katherine Anne Johnson, Anna L. Lippert, Sean G. Kraus, Grace E. McGrath, Philip B. Emmerich, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Wei Zhang, Dustin A. Deming
Publikováno v: Cancer Research. 82:3533-3533
Background: Cancer-associated fibroblasts (CAFs) are major regulators of the immune microenvironment and therapeutic response in colorectal cancer (CRC). Neutralizing their role in modulating the immune landscape could be the key to enhancing immunot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f37e6a7b1cba7bb1479f874e1e5b40f
https://doi.org/10.1158/1538-7445.am2022-3533
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje