Effect of initiating biologics compared to intensifying conventional DMARDs on clinical and MRI outcomes in established rheumatoid arthritis patients in clinical remission: Secondary analyses of the IMAGINE-RA trial

Autor: L Larsen, Torkell Ellingsen, Ole Rintek Madsen, Signe Møller-Bisgaard, Lykke Midtbøll Ørnbjerg, Niels Steen Krogh, Hanne Merete Lindegaard, Kim Hørslev-Petersen, Jan Alexander Villadsen, Daniel Glinatsi, Marcin Ryszard Kowalski, Kristian Stengaard-Pedersen, B Ejbjerg, Merete Lund Hetland, Oliver Hendricks, Philip Bennett, Bente Jensen, H.S. Thomsen, Ellen Margrethe Hauge, Morten Ilum Boesen, Jakob M Møller, Mikkel Østergaard, René dePont Christensen, A. H. Nielsen, Henning Bliddal, A G Jurik, Karsten Asmussen

Publikováno v: Møller-Bisgaard, S, Hørslev-Petersen, K, Ejbjerg, B, Hetland, M L, Christensen, R, Ørnbjerg, L M, Glinatsi, D, Møller, J M, Boesen, M, Stengaard-Pedersen, K, Madsen, O R, Jensen, B, Villadsen, J A, Hauge, E M, Bennett, P, Hendricks, O, Asmussen, K, Kowalski, M, Lindegaard, H, Bliddal, H, Krogh, N S, Ellingsen, T, Nielsen, A H, Larsen, L, Jurik, A G, Thomsen, H S & Østergaard, M 2022, ' Effect of initiating biologics compared to intensifying conventional DMARDs on clinical and MRI outcomes in established rheumatoid arthritis patients in clinical remission: Secondary analyses of the IMAGINE-RA trial ', Scandinavian Journal of Rheumatology, vol. 51, no. 4, pp. 268-278 . https://doi.org/10.1080/03009742.2021.1935312
Møller-Bisgaard, S, Hørslev-Petersen, K, Ejbjerg, B, Hetland, M L, Christensen, R, Ørnbjerg, L M, Glinatsi, D, Møller, J M, Boesen, M, Stengaard-Pedersen, K, Madsen, O R, Jensen, B, Villadsen, J A, Hauge, E M, Bennett, P, Hendricks, O, Asmussen, K, Kowalski, M, Lindegaard, H, Bliddal, H, Krogh, N S, Ellingsen, T, Nielsen, A H, Larsen, L, Jurik, A G, Thomsen, H S & Østergaard, M 2022, ' Effect of initiating biologics compared to intensifying conventional DMARDs on clinical and MRI outcomes in established rheumatoid arthritis patients in clinical remission : Secondary analyses of the IMAGINE-RA trial ', Scandinavian Journal of Rheumatology, vol. 51, no. 4, pp. 268–278 . https://doi.org/10.1080/03009742.2021.1935312

Objectives: To compare the effect of treat-to-target-based escalations in conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and biologics on clinical disease activity and magnetic resonance imaging (MRI) inflammation in a rheuma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f7dfe985183b4abe854c3316162c76
https://doi.org/10.1080/03009742.2021.1935312

Validity and Responsiveness of Combined Inflammation and Combined Joint Damage Scores Based on the OMERACT Rheumatoid Arthritis MRI Scoring System (RAMRIS)

Autor: Anna-Birgitte Aga, Kim Hørslev-Petersen, Kristian Stengard-Pedersen, Mikkel Østergaard, Daniel Glinatsi, Ulf Sundin, Philip G. Conaghan, Espen A Haavardsholm, Siri Lillegraven, B Ejbjerg, Peter Junker, Paul Bird, Merete Lund Hetland

Publikováno v: Sundin, U, Østergaard, M, Glinatsi, D, Aga, A B, Hørslev-Petersen, K, Hetland, M L, Stengaard-Pedersen, K, Junker, P, Ejbjerg, B J, Bird, P, Conaghan, P G, Lillegraven, S & Haavardsholm, E A 2019, ' Validity and responsiveness of combined inflammation and combined joint damage scores based on the OMERACT rheumatoid arthritis MRI scoring system (RAMRIS) ', Journal of Rheumatology, vol. 46, no. 9, pp. 1222-1227 . https://doi.org/10.3899/jrheum.181064
Sundin, U, Østergaard, M, Glinatsi, D, Aga, A-B, Hørslev-Petersen, K, Hetland, M L, Stengard-Pedersen, K, Junker, P, Ejbjerg, B J, Bird, P, Conaghan, P G, Lillegraven, S & Haavardsholm, E A 2019, ' Validity and Responsiveness of Combined Inflammation and Combined Joint Damage Scores Based on the OMERACT Rheumatoid Arthritis MRI Scoring System (RAMRIS) ', Journal of Rheumatology, vol. 46, no. 9, pp. 1222-1227 . https://doi.org/10.3899/jrheum.181064

Objective.The RAMRIS [Outcome Measures in Rheumatology rheumatoid arthritis (RA) magnetic resonance imaging (MRI) Scoring system] is used in clinical RA trials. We have investigated methods to combine the RAMRIS features into valid and responsive sco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3b9958db3375b90fa94027fc18e184
https://doi.org/10.3899/jrheum.181064

OP0331 MAGNETIC RESONANCE IMAGING TENOSYNOVITIS AND OSTEITIS ARE INDEPENDENT PREDICTORS OF RADIOGRAPHIC AND MRI DAMAGE PROGRESSION IN RHEUMATOID ARTHRITIS PATIENTS IN CLINICAL REMISSION

Autor: Lykke Midtbøll Ørnbjerg, Mikkel Østergaard, Ole Rintek Madsen, Agnete Desirée Nielsen, Philip Bennett, Bente Jensen, Jan Alexander Villadsen, Daniel Glinatsi, Oliver Hendricks, Marcin Ryszard Kowalski, Kristian Stengaard-Pedersen, Kim Hørslev-Petersen, Henrik S. Thomsen, Torkell Ellingsen, Mikael Boesen, Ellen Margrethe Hauge, B Ejbjerg, Signe Møller-Bisgaard, Jakob M Møller, Henning Bliddal, Niels Steen Krogh, Lone Balding, Merete Lund Hetland, Hanne Merete Lindegaard, Karsten Asmussen, Anne Grethe Jurik

Publikováno v: Oral Presentations.

Background Progression of structural joint damage occurs in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Magnetic resonance imaging (MRI)-detected synovitis and in particular osteitis/bone marrow edema (BME) are known pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42a93a3a3498b18137d6cca245ac8921
https://doi.org/10.1136/annrheumdis-2019-eular.2006

OP0018 The value of adding mri to a clinical treat-to-target strategy in rheumatoid arthritis patients in clinical remission: clinical and radiographic outcomes from the imagine-ra randomised controlled trial

Autor: Anne Grethe Jurik, Ole Rintek Madsen, Lykke Midtbøll Ørnbjerg, B Ejbjerg, Morten Ilum Boesen, Henning Bliddal, Daniel Glinatski, Mikkel Østergaard, Sabrina Mai Nielsen, Jan Alexander Villadsen, Kristian Stengaard-Pedersen, Marcin Ryszard Kowalski, Jakob M Møller, P. Bennet, Hanne Merete Lindegaard, A. H. Nielsen, Kim Hørslev-Petersen, Bente Jensen, Niels Steen Krogh, Lone Balding, Ellen Margrethe Hauge, Oliver Hendricks, Signe Møller-Bisgaard, Merete Lund Hetland, Torkell Ellingsen, Karsten Asmussen, Henrik S. Thomsen, René dePont Christensen

Publikováno v: WEDNESDAY, 13 JUNE 2018.

Background Targeting MRI remission in rheumatoid arthritis (RA) patients in clinical remission may improve clinical outcome and halt joint damage progression. Objectives To determine whether a treat-to-target (T2T) strategy based on structured MRI as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fc8fec3acf713776dcc64d7d9140cbd
https://doi.org/10.1136/annrheumdis-2018-eular.1204

An introduction to the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas

Autor: Mikkel Østergaard, Harry K. Genant, P.G. Conaghan, F McQueen, Charles Peterfy, Paul Bird, B Ejbjerg, Paul Emery, Marissa Lassere, John Edmonds

Publikováno v: Annals of the Rheumatic Diseases. 64:i3-i7

This article gives a short overview of the development and characteristics of the OMERACT rheumatoid arthritis MRI scoring system (RAMRIS), followed by an introduction to the use of the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas. Wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b6979a46694d335b0b13a32f963a66
https://doi.org/10.1136/ard.2004.031773