Zobrazeno 1 - 10
of 16
pro vyhledávání: '"B E Torbett"'
Publikováno v:
The Journal of Immunology. 153:4826-4833
The ability to infect human peripheral blood leukocyte-reconstituted severe combined immunodeficient (hu-PBL-SCID) mice with HIV has allowed evaluation of several strategies for preventing or treating infection. In one study, hu-PBL-SCID mice derived
Publikováno v:
Blood. 80:1717-1724
We show here for the first time that pluripotent hematopoietic stem cells express the CD4 antigen. CD4+ cells isolated from mouse marrow repopulated all hematopoietic lineages in both the long-term repopulation assay and the competitive repopulation
Autor:
D N Ernst, M V Hobbs, B E Torbett, A L Glasebrook, M A Rehse, K Bottomly, K Hayakawa, R R Hardy, W O Weigle
Publikováno v:
The Journal of Immunology. 145:1295-1302
Previous studies indicate that the 3G11, CD45RB, and Pgp-1 determinants are differentially expressed on CD4+ T cell subsets in the mouse. We used multicolor immunofluorescence staining and flow cytofluorometric analysis to examine the expression of e
Autor:
A J, Pelletier, L J, van der Laan, P, Hildbrand, M A, Siani, D A, Thompson, P E, Dawson, B E, Torbett, D R, Salomon
Publikováno v:
Blood. 96(8)
The role of chemokine-matrix interactions in integrin-dependent T-cell migration was examined to address the critical question of how chemokines provide directional information. The chemokine SDF-1 alpha binds fibronectin (Fn) with a low nanomolar K(
Publikováno v:
Blood. 94(11)
There is growing interest in using human umbilical cord blood (CB) for allogeneic bone marrow transplantation (BMT), particularly in children. Thus, CB has been identified as a rich source of hematopoietic progenitors of the erythroid, myeloid, and B
Autor:
K L, Anderson, K A, Smith, H, Perkin, G, Hermanson, C G, Anderson, D J, Jolly, R A, Maki, B E, Torbett
Publikováno v:
Blood. 94(7)
PU.1 is a hematopoietic cell-specific ets family transcription factor. Gene disruption of PU.1 results in a cell autonomous defect in hematopoietic progenitor cells that manifests as abnormal myeloid and B-lymphoid development. Of the myeloid lineage
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(4)
IL-18 is expressed from a variety of cell types. Two promoters located upstream of exon 1 (5'-flanking region) and upstream of exon 2 (intron 1) regulate its expression. Both promoter regions were cloned into pCAT-Basic plasmid to yield p1-2686 for t
Publikováno v:
Blood. 91(10)
The ets family transcription factor PU.1 is expressed in monocytes/macrophages, neutrophils, mast cells, B cells, and early erythroblasts, but not in T cells. We have recently shown that PU.1 gene disruption results in mice with no detectable monocyt
Autor:
S R, McKercher, B E, Torbett, K L, Anderson, G W, Henkel, D J, Vestal, H, Baribault, M, Klemsz, A J, Feeney, G E, Wu, C J, Paige, R A, Maki
Publikováno v:
The EMBO journal. 15(20)
PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a disruption in the PU.1 DNA binding domain are born alive but die of severe septicemia within 48 h. T
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(10)
The ability to infect human peripheral blood leukocyte-reconstituted severe combined immunodeficient (hu-PBL-SCID) mice with HIV has allowed evaluation of several strategies for preventing or treating infection. In one study, hu-PBL-SCID mice derived