Zobrazeno 1 - 10 of 15 pro vyhledávání: '"B E Korba"'
1
Cyclosporin A modulates the course of woodchuck hepatitis virus infection and induces chronicity
Autor: P J Cote, B E Korba, H Steinberg, C Ramirez-Mejia, B Baldwin, W E Hornbuckle, B C Tennant, J L Gerin
Publikováno v: The Journal of Immunology. 146:3138-3144
Immunosuppression is known to influence the state of chronic hepatitis B virus infection, and is thought to increase the risk of developing chronic infection in newly exposed individuals. Cyclosporin A (CsA), an immunosuppressive agent that inhibits
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af43487ea21c334713b1dfbebd5e750b
https://doi.org/10.4049/jimmunol.146.9.3138
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2
Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks
Autor: B E, Korba, P, Cote, W, Hornbuckle, R, Schinazi, J D, Gangemi, B C, Tennant, J L, Gerin
Publikováno v: Antiviral therapy. 5(2)
Cell culture studies in our laboratory previously demonstrated synergistic antiviral activity for the combinations of lamivudine and a novel recombinant hybrid human alpha B/D interferon (rHu alpha B/D IFN) against hepatitis B virus (HBV) replication
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::921c4baf31209ce694a09bb5e5164db9
https://pubmed.ncbi.nlm.nih.gov/10971862
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3
Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent
Autor: C K, Chu, F D, Boudinot, S F, Peek, J H, Hong, Y, Choi, B E, Korba, J L, Gerin, P J, Cote, B C, Tennant, Y C, Cheng
Publikováno v: Antiviral therapy. 3(Suppl 3)
Preclinical aspects of a potent anti-hepatitis B virus (HBV) L-nucleoside, 1-(2-fluoro-5-methyl-beta-L-arabino-furanosyl)uracil (L-FMAU) are described. L-FMAU was prepared from L-ribose derivatives via either L-xylose or L-arabinose. L-FMAU shows pot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e4a3c80246c93874dc85fb5ce112b609
https://pubmed.ncbi.nlm.nih.gov/10726061
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4
Transgenic mice as a chemotherapeutic model for hepatitis B virus infection
Autor: J D, Morrey, B E, Korba, R W, Sidwell
Publikováno v: Antiviral therapy. 3(Suppl 3)
Many transgenic mice carrying either portions of the hepatitis B virus (HBV) genome, or the complete genome, have been developed as models because HBV does not infect any other organisms besides humans and chimpanzees to cause a productive infection
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce878b554ed228ac83b71a463529a53f
https://pubmed.ncbi.nlm.nih.gov/10726056
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5
The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir
Autor: C, Périgaud, G, Gosselin, J L, Girardet, B E, Korba, J L, Imbach
Publikováno v: Antiviral research. 40(3)
The synthesis and in vitro anti-hepatitis B virus (HBV) activity of two mononucleoside phosphotriester derivatives of acyclovir incorporating S-acyl-2-thioethyl (SATE) groups are reported. In contrast to the parent nucleoside, the described phosphotr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45c482c5af63c06bd4c69d4757a4e9f4
https://pubmed.ncbi.nlm.nih.gov/10027651
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7
Hepatocellular carcinoma in Richardson's ground squirrels (Spermophilus richardsonii): evidence for association with hepatitis B-like virus infection
Autor: B C, Tennant, N, Mrosovsky, K, McLean, P J, Cote, B E, Korba, R E, Engle, J L, Gerin, J, Wright, G R, Michener, E, Uhl
Publikováno v: Hepatology (Baltimore, Md.). 13(6)
During studies of seasonal obesity, a high frequency of hepatic neoplasms was observed in Richardson's ground squirrels. Of 12 Richardson's ground squirrels examined thoroughly, 7 had mild or moderate degrees of chronic portal hepatitis and 6 (50%) h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8e6b4901690a5df445ae66d045a1c79
https://pubmed.ncbi.nlm.nih.gov/1646762
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9
Retraction: DNA from recombinogenic bacteriophages generated by arl mutant of Escherichia coli is cleaved by a single-strand-specific endonuclease S1
Autor: J B Hays, B E Korba
When propagated on arl strains (a subclass of Escherichia coli hyper-rec mutants), lambda "Red-" duplication phages accumulated an enhanced potential for recombination. The physical properties of the recombinogenic phages thus obtained ("Arl-" phages
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df09145ee0a994aa73eb845388206d1e
https://europepmc.org/articles/PMC397166/
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10
Hepadnavirus-induced liver cancer in woodchucks
Autor: J L, Gerin, P J, Cote, B E, Korba, B C, Tennant
Publikováno v: Cancer detection and prevention. 14(2)
Woodchuck hepatitis virus (WHV), a member of the Hepadnaviridae, is closely related to hepatitis B virus (HBV) in its virus structure, genetic organization, and mechanism of replication. As with HBV in man, persistent WHV infection is common in natur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a719252c9a66d62ff756f1a7d2c68887
https://pubmed.ncbi.nlm.nih.gov/2695243
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