Zobrazeno 1 - 10
of 26
pro vyhledávání: '"B E Britigan"'
Publikováno v:
The Journal of Immunology. 157:5009-5015
Human peripheral blood eosinophils generate superoxide (O2.-) in response to PMA stimulation. These cells are also capable of forming the highly reactive hydroxyl radical (HO.) by a process that is dependent on the presence of active eosinophil perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3689ece664f5e9158639d4d102d2d75d
https://doi.org/10.4049/jimmunol.157.11.5009
https://doi.org/10.4049/jimmunol.157.11.5009
Publikováno v:
The Journal of Immunology. 153:2691-2703
The iron content of tissue macrophages increases under conditions of elevated extracellular iron. Studies of macrophage iron acquisition have generally focused on iron uptake from transferrin via receptor-mediated endocytosis. However, in vivo macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fec4c14d25c701611b1c260746889c1
https://doi.org/10.4049/jimmunol.153.6.2691
https://doi.org/10.4049/jimmunol.153.6.2691
Autor:
M L, McCormick, G M, Denning, K J, Reszka, P, Bilski, G R, Buettner, G T, Rasmussen, M A, Railsback, B E, Britigan
Publikováno v:
The Biochemical journal.
Because cell-mediated reduction of menadione leads to the generation of reactive oxygen species (ROS), this quinone is widely used to investigate the effects of ROS on cellular functions. We report that A549 human lung epithelial cells exposed to men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37a2a1f6b1c97ce96d17455a52e15782
https://pubmed.ncbi.nlm.nih.gov/10970795
https://pubmed.ncbi.nlm.nih.gov/10970795
Publikováno v:
Advances in experimental medicine and biology. 443
Previous work has demonstrated the ability of the promastigote form of the protozoan parasite Leishmania chagasi to utilize iron chelated to lactoferrin and transferrin for growth and metabolism. We have obtained evidence suggesting that the promasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b2e5092781cdc25bd9de834d38d74dc
https://pubmed.ncbi.nlm.nih.gov/9781352
https://pubmed.ncbi.nlm.nih.gov/9781352
Autor:
B, de Andres, E, Rakasz, M, Hagen, M L, McCormik, A L, Mueller, D, Elliot, A, Metwali, M, Sandor, B E, Britigan, J V, Weinstock, R G, Lynch
Publikováno v:
Blood. 89(10)
Chronic infection with Schistosoma mansoni induces in humans and mice a Th2-dominant immune response in which eosinophils and IgE are conspicuously elevated. Human eosinophils express IgE receptors that participate in an IgE-dependent eosinophil-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0356974cb6b205173e1511423987eec
https://pubmed.ncbi.nlm.nih.gov/9160653
https://pubmed.ncbi.nlm.nih.gov/9160653
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(11)
Human peripheral blood eosinophils generate superoxide (O2.-) in response to PMA stimulation. These cells are also capable of forming the highly reactive hydroxyl radical (HO.) by a process that is dependent on the presence of active eosinophil perox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdff0a7a0b5c8208eb59dae4af25e282
https://pubmed.ncbi.nlm.nih.gov/8943408
https://pubmed.ncbi.nlm.nih.gov/8943408
Publikováno v:
The Journal of biological chemistry. 270(49)
The iron chelator deferoxamine (Desferal; DSFL) reacts with peroxidases and H2O2 to form the DSFL radical (DSFL.), which can be detected by EPR spectroscopy. We have found that DSFL. formation resulting from exposure to H2O2 and any of a number of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16c092bf3c12fe5ce10d08a532ab1f41
https://pubmed.ncbi.nlm.nih.gov/7493957
https://pubmed.ncbi.nlm.nih.gov/7493957
Autor:
R A, Miller, B E, Britigan
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 43(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bee1819b77691303c58d86e736b0a7e8
https://pubmed.ncbi.nlm.nih.gov/7719758
https://pubmed.ncbi.nlm.nih.gov/7719758
Publikováno v:
The Journal of biological chemistry. 269(45)
Eosinophil production of superoxide (O2-.) and hydrogen peroxide (H2O2) is important in host defense. The present study assessed the potential of eosinophils to generate another potent cytotoxic species, the hydroxyl radical (.OH). .OH formation by p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ed747ce29769359e306438cf8a19947
https://pubmed.ncbi.nlm.nih.gov/7961724
https://pubmed.ncbi.nlm.nih.gov/7961724
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(6)
The iron content of tissue macrophages increases under conditions of elevated extracellular iron. Studies of macrophage iron acquisition have generally focused on iron uptake from transferrin via receptor-mediated endocytosis. However, in vivo macrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76c5bd6b5fa310401a01050f91ffcdf3
https://pubmed.ncbi.nlm.nih.gov/8077675
https://pubmed.ncbi.nlm.nih.gov/8077675