Zobrazeno 1 - 10
of 106
pro vyhledávání: '"B E, Weissman"'
Ews/Fli-1 Chimeric Oncogene: Role in Neuronal Differentiation and Abrogation of p53 A Two-Year Study
Autor:
B. E. Weissman, C. J. Rorie
Publikováno v:
Minority Trainee Research Forum, 2004.
Autor:
B. T. Hummer, B. E. Weissman, Juan Juan Yin, Theresa A. Guise, Susan M Padalecki, Korri S. Weldon, Mark Dallas, Barry Grubbs, Devon C. Hall, Xavier T. Reveles, Robin J. Leach, Teresa L. Johnson-Pais, Y. Cui, C. L. Buller
Publikováno v:
Urologic oncology. 21(5)
Loss of heterozygosity and allelic imbalance data has shown that there are two distinct regions of loss on chromosome 18q associated with the progression of prostate cancer (CaP). To investigate the functional significance of chromosome 18q loci in C
Publikováno v:
Journal of cellular physiology. 186(1)
Organization of genomic DNA into chromatin aids in the regulation of gene expression by limiting access to transcriptional machinery. The SWI/SNF family of complexes, which are conserved from yeast to humans, are ATP-dependent chromatin-remodeling en
Autor:
M E, Miele, M D, Jewett, S F, Goldberg, D L, Hyatt, C, Morelli, F, Gualandi, P, Rimessi, D J, Hicks, B E, Weissman, G, Barbanti-Brodano, D R, Welch
Publikováno v:
International journal of cancer. 86(4)
Loss, deletion or rearrangement along large portions of the long arm (q-arm) of chromosome 6 occurs in80% of late-stage human melanomas, suggesting that genes controlling malignant characteristics are encoded there. Metastasis, but not tumorigenicity
Publikováno v:
Molecular carcinogenesis. 25(1)
Using a series of tumorigenic and non-tumorigenic somatic cell hybrids that resulted from the fusion of the human osteosarcoma cell line OHS50-P16T (P16T) with the HeLa cell line D98OR, we investigated the role that genetic mutations, including alter
Publikováno v:
Molecular carcinogenesis. 24(1)
The oncogenic human papillomaviruses (HPVs) are able to efficiently target p53 for degradation by the ubiquitin pathway. We previously demonstrated inefficient HPV E6-mediated degradation and resulting high steady-state levels of p53 in cell hybrids
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(7)
Neuroblastoma (NB) cells in vitro are capable of bidirectional transdifferentiation, resulting in two distinct, yet reversible, phenotypes of neuroblastic (N-type) and nonneuronal (S-type) Schwann-like cells. Our previous studies suggested that the w
Publikováno v:
Molecular carcinogenesis. 21(2)
Using microcell-mediated transfer of a normal chromosome 11 into the highly metastatic MDA-MB-435 human breast carcinoma cell line, we previously showed that human chromosome 11 contains a metastasis-suppressor gene for breast cancer. A known metasta
Publikováno v:
Genes, chromosomescancer. 20(2)
By somatic cell hybridization, amplification has been found to be a recessive genetic trait in three tumor cell lines examined. Studies with transgenic mice have shown that amplification frequency can be altered by a lack of wild-type TP53 (p53) acti
Autor:
W B, Coleman, G L, Esch, K M, Borchert, K D, McCullough, L H, Reid, B E, Weissman, G J, Smith, J W, Grisham
Publikováno v:
Molecular carcinogenesis. 19(4)
We previously demonstrated that a locus (or loci) linked to the D11S436 marker, which is within the approximately 6-Mb cen-p12 region of human chromosome 11, suppresses the tumorigenic potential of some rat liver epithelial tumor microcell hybrid (MC