Zobrazeno 1 - 8
of 8
pro vyhledávání: '"B E, Markham"'
Autor:
J D Molkentin, B E Markham
Publikováno v:
Molecular and Cellular Biology. 14:5056-5065
Cardiac muscle-restricted expression of the alpha-myosin heavy-chain (alpha-MHC) gene is regulated by multiple elements in the proximal enhancer/promoter. Within this region, an M-CAT site and an A-rich site were identified as potential regulatory el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c04bf9f0058c76b021de7d079d53d7
https://doi.org/10.1128/mcb.14.8.5056
https://doi.org/10.1128/mcb.14.8.5056
Autor:
J D, Molkentin, B E, Markham
Publikováno v:
The Journal of biological chemistry. 268(26)
A myocyte-specific enhancer-binding factor (MEF-2) DNA binding site was identified in the rat alpha-myosin heavy chain (MHC) gene adjacent to the E-box binding site for alpha-MHC binding factor-2 (BF-2). Mutation of the MEF-2 site, within the context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ff626059aa4416185b382906a5ebc91
https://pubmed.ncbi.nlm.nih.gov/8366095
https://pubmed.ncbi.nlm.nih.gov/8366095
Publikováno v:
The Journal of biological chemistry. 268(4)
Proximal regulatory element B (PRE-B), located from positions -318 to -284 in the alpha-myosin heavy chain (MHC) promoter, stimulated expression from an otherwise weak alpha-MHC promoter fragment in primary rat neonatal cardiomyocytes but not in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52d0f7c503bfe1f6861ea2024d5d8aca
https://pubmed.ncbi.nlm.nih.gov/8428936
https://pubmed.ncbi.nlm.nih.gov/8428936
Publikováno v:
The Journal of biological chemistry. 265(11)
The effects of thyroid hormone on expression of cardiac myosin heavy chain genes generally are thought to be mediated by nuclear 3,5,3'-triiodo-L-thyronine (T3) receptors that have been identified as the products of the protooncogene, c-erbA. This hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2597f32d1822e08737e763f2079d4ae0
https://pubmed.ncbi.nlm.nih.gov/1690729
https://pubmed.ncbi.nlm.nih.gov/1690729
Publikováno v:
Proceedings of the National Academy of Sciences. 84:3122-3126
In ventricular muscle, 3,5,3'-triiodo-L-thyronine (T3) stimulates the expression of the alpha-myosin heavy-chain (alpha-MHC) gene. To test for gene elements required for induction, a fragment of the alpha-MHC gene containing 2.9 kilobases of 5' flank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a68c74514c871d945efe2e8ec61e610
https://doi.org/10.1073/pnas.84.10.3122
https://doi.org/10.1073/pnas.84.10.3122
Autor:
B E Markham, R R Brubaker
The antitumor agent cis-platinum(II)diamminodichloride (PDD) caused wild-type and recA+ deoxyribonucleic acid (DNA) repair-deficient mutant cells of Escherichia coli K-12 to grow as long, multinucleated filaments. At 5 micrograms/ml, the times requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71e1da8ee074dac3dd001770636f42d
https://europepmc.org/articles/PMC294270/
https://europepmc.org/articles/PMC294270/
Publikováno v:
The Journal of biological chemistry. 262(26)
Using a gel mobility-shift assay, a nuclear protein factor was identified in cardiac myocyte which binds specifically to a DNA fragment from the 5' region of the alpha-myosin heavy chain gene shown previously to contain a thyroid hormone-sensitive el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::727ff5ddcdf1cdb0c978f64df729190f
https://pubmed.ncbi.nlm.nih.gov/3624281
https://pubmed.ncbi.nlm.nih.gov/3624281
Publikováno v:
The Journal of biological chemistry. 262(27)
Thyroid hormone regulates the expression of ventricular myosin isoenzymes by causing an accumulation of alpha-myosin heavy chain (MHC) mRNA and inhibiting expression of beta-MHC mRNA. However, the mechanism of thyroid hormone action has been difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc6b5a42011202edc72aef2eed73350f
https://pubmed.ncbi.nlm.nih.gov/2888758
https://pubmed.ncbi.nlm.nih.gov/2888758