Zobrazeno 1 - 10
of 113
pro vyhledávání: '"B E, Kosofsky"'
Publikováno v:
Magnetic resonance in medicine. 45(3)
Functional MRI of rat brain was performed at 2 Tesla following intravenous injection of cocaine in order to 1) determine if changes in CBV and changes in BOLD signal were regionally coupled in brain parenchyma, and 2) compare the sensitivities of the
Autor:
C J, Malanga, B E, Kosofsky
Publikováno v:
Clinics in perinatology. 26(1)
The consequences of public health of the acquisition and use of drugs of abuse have been well demonstrated. Despite intense effort, however, progress has been slow in recent years in ascertaining the specific neurodevelopmental effects of these drugs
Autor:
B E, Kosofsky, A S, Wilkins
Publikováno v:
Annals of the New York Academy of Sciences. 846
To characterize the effects of cocaine on developing brain we have developed a mouse model of gestational cocaine exposure. We studied pregnant dams injected twice daily with cocaine HCl at 40, 20, or 10 mg/kg/day sc from embryonic days (E)8 to E17 (
Autor:
B E, Kosofsky
Publikováno v:
Journal of women's health. 7(5)
Publikováno v:
Neurotoxicology and teratology. 20(3)
In a mouse model of transplacental cocaine exposure we have demonstrated alterations in brain structure and function of offspring including disturbances of brain growth, disruption of neocortical cytoarchitecture, and transient as well as persistent
Publikováno v:
Neurotoxicology and teratology. 20(3)
We have utilized a mouse model of transplacental cocaine exposure to investigate the effects of cocaine dose and gestational timing in altering brain and body growth and postnatal behavior in exposed offspring. Pregnant dams were injected with cocain
Autor:
E W, Johnson, L M, Iyer, S S, Rich, H T, Orr, A, Gil-Nagel, J H, Kurth, J M, Zabramski, D A, Marchuk, J, Weissenbach, C L, Clericuzio, L E, Davis, B L, Hart, J F, Gusella, B E, Kosofsky, D N, Louis, L A, Morrison, E D, Green, J L, Weber
Publikováno v:
Genome research. 5(4)
Cerebral cavernous malformations (CCM) are vascular lesions present in some 20 million people worldwide that are responsible for seizures, migraine, hemorrhage, and other neurologic problems. Familial cases ofCCM can be inherited as an autosomal domi
Publikováno v:
NIDA research monograph. 125
It is probably safe to say that the regulation of c-fos expression by drug treatment and other stimulus paradigms has biological specificity and mechanistic significance. However, as this brief essay makes clear, the immunohistochemical detection of
Autor:
B E, Kosofsky, S E, Hyman
Publikováno v:
NIDA research monograph. 125
Autor:
B E, Kosofsky
Publikováno v:
NIDA research monograph. 114