Zobrazeno 1 - 10
of 72
pro vyhledávání: '"B E, Kemp"'
Publikováno v:
Journal of Biological Chemistry. 269:6603-6607
NIMA is a cell cycle-regulated protein kinase required for the G2/M transition in the filamentous fungus Aspergillus nidulans. Previous biochemical characterization of the recombinant enzyme indicated that NIMA is a protein serine/threonine specific
Publikováno v:
Clinical and Experimental Immunology. 90:6-12
SUMMARY A characteristic feature associated with HIV-1 infection of the human host is a chronic decline in circulating CD4+ T helper/inducer cell numbers. Impaired cell-mediated immune functions usually occur in parallel with the decline in CD4+ T ce
Autor:
S M, Turpin, J G, Ryall, R, Southgate, I, Darby, A L, Hevener, M A, Febbraio, B E, Kemp, G S, Lynch, M J, Watt
Publikováno v:
The Journal of physiology. 587(Pt 7)
Excess lipid accumulation resulting from an elevated supply of plasma fatty acids is linked to the pathogenesis of the metabolic syndrome and heart disease. The term 'lipotoxicity' was coined to describe how lipid accumulation leads to cellular dysfu
Publikováno v:
Proceedings of the National Academy of Sciences. 88:5734-5738
A monoclonal anti-idiotype antibody, NS7, previously shown to mimic the binding of the pterin cofactor of phenylalanine hydroxylase (phenylalanine 4-monooxygenase, EC 1.14.16.1) has been used to localize the cofactor binding site within the phenylala
Publikováno v:
The Journal of biological chemistry. 276(9)
A novel human plasma protein has been identified as a universal component of complement deposits, when complement is detected immunohistochemically in vivo. The protein is homologous to complement factor H and related proteins and has been designated
Autor:
B, Kobe, I G, Jennings, C M, House, B J, Michell, K E, Goodwill, B D, Santarsiero, R C, Stevens, R G, Cotton, B E, Kemp
Publikováno v:
Nature structural biology. 6(5)
Phenylalanine hydroxylase converts phenylalanine to tyrosine, a rate-limiting step in phenylalanine catabolism and protein and neurotransmitter biosynthesis. It is tightly regulated by the substrates phenylalanine and tetrahydrobiopterin and by phosp
Autor:
K A, Anderson, R L, Means, Q H, Huang, B E, Kemp, E G, Goldstein, M A, Selbert, A M, Edelman, R T, Fremeau, A R, Means
Publikováno v:
The Journal of biological chemistry. 273(48)
Ca2+/calmodulin-dependent protein kinases I and IV (CaMKI and CaMKIV, respectively) require phosphorylation on an equivalent single Thr in the activation loop of subdomain VIII for maximal activity. Two distinct CaMKI/IV kinases, CaMKKalpha and CaMKK
Publikováno v:
Journal of virology. 71(7)
Hetero-oligomerization between human immunodeficiency virus type 2 (HIV-2) envelope glycoprotein (Env) truncation mutants and epitope-tagged gp160 is dependent on the presence of gp41 transmembrane protein (TM) amino acids 552 to 589, a putative amph
Publikováno v:
Journal of virology. 71(3)
Human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) oligomerization was investigated by coexpressing wild-type and truncated envelope glycoproteins to determine the minimum sequence required for mutant-wild-type hetero-oligomeriza
Publikováno v:
Advances in second messenger and phosphoprotein research. 31