Výsledky vyhledávání

Accumulation of an inactive form of p53 protein in cells treated with TNFα

Autor: P Drané, V Leblanc, R Saffroy, Evelyne May, F Miro-Mur, B Debuire

Publikováno v: Cell Death & Differentiation. 9:527-537

In MCF-7 cells, TNF alpha induces a G1 arrest with an increased expression of p21/Waf1, an activation of NF-kappa B and an accumulation of p53. NF-kappa B and p53 are two transcriptional factors known to activate p21/Waf1 gene expression. Here we sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb51fdf0373ca73d4772eab21f4f5f87
https://doi.org/10.1038/sj.cdd.4400983

Zobrazit plný text záznamu

Real-time quantitation of bcr-abl transcripts in haematological malignancies

Autor: A Lemoine, Raphaël Saffroy, P. Brezillon, G. Nedellec, B Debuire, E. Goldschmidt, N. Frenoy, B. Souleau, B. Delmas

Publikováno v: European Journal of Haematology. 65:258-266

We have applied an automated real-time quantitative PCR assay using a double-labeled fluorogenic probe to detect t(9;22)-positive cells in haematological malignancies. The results are expressed as the ratio of chimeric bcr-abl transcripts on abl tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2fddad168da27c52a2d6667a713fbb9
https://doi.org/10.1034/j.1600-0609.2000.065004258.x

Zobrazit plný text záznamu

Protéine P53: applications cliniques

Autor: B. Debuire

Publikováno v: Revue Française des Laboratoires. 1996:59-63

Resume L'interet concernant le gene et la proteine P53 est alle croissant au cours des cinq dernieres annees. Il est maintenant bien connu que les alterations de p53 sont frequentes dans les cancers humains et qu'elles representent une etape importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41da6b958c10ca3b7894b8755b2f8ea8
https://doi.org/10.1016/s0338-9898(96)80030-8

Zobrazit plný text záznamu

Nonisotopic competitive RT-PCR assay to measure MDR1 gene expression

Autor: O. Sol, E May, B Debuire, Antoinette Lemoine

Publikováno v: Clinical Chemistry. 41:819-825

We report an original application of competitive reverse transcription-polymerase chain reaction (RT-PCR) for the quantification of MDR1 mRNA in clinical specimens by simultaneous reverse transcription and PCR amplification of cellular RNA with decre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dfddab8217bdde1392c091f82116e98
https://doi.org/10.1093/clinchem/41.6.819

Zobrazit plný text záznamu

Molecular analysis of lymphoid malignancies

Autor: N, Frenoy, M, Gildelgado, P, Pham, M, Salvucci, A, Chahine, A, Chabli, J, Misset, B, Debuire

Publikováno v: Oncology reports. 3(2)

Although lymphoid malignancies have been widely studied at the molecular level, no group has reported on the simultaneous investigation of t(14;18) chromosomal translocation, B-cell clonality and bcl2 gene expression. We have performed PCR analysis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::00fe616e2b5e0666676f41f771f09966
https://pubmed.ncbi.nlm.nih.gov/21594379

Zobrazit plný text záznamu

CTNNB1 (catenin, beta-1)

Autor: B Debuire, A Lemoine, R Saffroy