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Current thinking on chronic renal allograft rejection: Issues, concerns, and recommendations from a 1997 roundtable discussion

Autor: Jimmy A. Light, B D Kahan, Arthur J. Matas, Kim Solez, James F. Burke, Philip F. Halloran, Ronald M. Ferguson, Anthony P. Monaco

Publikováno v: American Journal of Kidney Diseases. 33:150-160

Chronic rejection accounts for most renal allograft losses after the first year posttransplantation. On March 24 and 25, 1997, a roundtable of five transplant surgeons, two nephrologists, and one pathologist assembled in Dallas, Texas, to review crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcefc1b8f84101235a1d322686fc70a
https://doi.org/10.1016/s0272-6386(99)70273-8

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PROTECTION AGAINST ALLOGRAFT REJECTION WITH INTERCELLULAR ADHESION MOLECULE-1 ANTISENSE OLIGODEOXYNUCLEOTIDES1

Autor: K. Stecker, Mark J. Graham, Ling Tian, M-E Wang, Xiumei Qu, B. D. Kahan, Stanislaw M. Stepkowski, Wenhao Chen, C. F. Bennett, T. P. Condon, S. Cheng-Flournoy

Publikováno v: Transplantation. 66:699-707

BACKGROUND: We designed an antisense phosphorothioate oligodeoxynucleotide (oligo) to specifically inhibit the expression of rat intercellular adhesion molecule-1 (ICAM-1) mRNA (IP-9125). METHODS: IP-9125 oligo was delivered intravenously by osmotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa7c609f773a1c669b9c8910cd24630d
https://doi.org/10.1097/00007890-199809270-00003

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Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry

Autor: Hans-Martin Schiebel, B D Kahan, K F Sewing, F Streit, Uwe Christians, A Linck, L Ernst, K L Napoli

Publikováno v: Scopus-Elsevier

Sirolimus (rapamycin) has a macrolide structure and is under clinical investigation as an immunosuppressant after organ transplantation. An HPLC/mass spectrometry assay to quantify sirolimus in blood was developed. 28-O-Acetyl sirolimus was used as i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b3dcc15f366925d22c40f78278fbd8
https://doi.org/10.1093/clinchem/42.9.1417

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A Trial of the Prostaglandin E1 Analogue, Enisoprost, to Reverse Chronic Cyclosporine-Associated Renal Dysfunction

Autor: M. Cole, M. Moran, V. Hyndman, R. Lewis, S. Veremis, M. F. Mozes, R. Pollak, E. Scott, M. Maddux, B. D. Kahan, C. Van Buren, Richard J. Knight

Publikováno v: American Journal of Kidney Diseases. 20:336-341

Cyclosporine (CYA) reduces the renal synthesis of prostaglandins of the E series (PGE). Analogue of PGE, have been shown to mitigate the vasoconstriction and abnormal renal function of experimental acute CYA nephrotoxicity. We examined the hypothesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534ff01cd2c0f3ca14f3506f192ce52b
https://doi.org/10.1016/s0272-6386(12)70295-0

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The ruby anniversary: forty years of publication of Transplantation Proceedings - the first decade: the flowering of immunology and immunogenetics

Autor: B D, Kahan

Publikováno v: Transplantation proceedings. 41(1)

The fortieth-ruby-anniversary of publication of Transplantation Proceedings chronicles the major developments in this field of expanding scientific and clinical importance. The first decade of publication included seminal findings in immunogenetics o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98f3ad88dc718df6b98df70a47a0d37f
https://pubmed.ncbi.nlm.nih.gov/19249461

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Area Under the Curve Monitoring of Cyclosporine Therapy

Autor: Joachim Grevel, B. D. Kahan

Publikováno v: Therapeutic Drug Monitoring. 13:89-95

Summary: The impact of a new monitoring strategy on whole blood concentrations of cyclosporine measured by a specific monoclonal radioimmunoassay was investigated in a group of 37 renal transplant patients. Before transplantation, the patients receiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2f4090b9fef315ff73db1bf3af6481
https://doi.org/10.1097/00007691-199103000-00001

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Selective corticosteroid and calcineurin-inhibitor withdrawal after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy

Autor: R J, Knight, R H, Kerman, E, McKissick, A, Lawless, H, Podder, S, Katz, C T, Van Buren, B D, Kahan

Publikováno v: Clinical transplantation. 22(5)

Of 25 simultaneous pancreas-kidney transplant (SPK) recipients treated with thymoglobulin induction, sirolimus and reduced-dose cyclosporine (CsA), 18 low-immune responders (non-African-Americans, PRA30%) were withdrawn from prednisone on post-transp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4607e9ff9299f382043ca99df576ecc8
https://pubmed.ncbi.nlm.nih.gov/18657156

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