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Autor: B. E. Roberts, M. J. Mcmahon, B. D. Griffin, I. E. Burton

Publikováno v: Scandinavian Journal of Haematology. 25:127-133

A study of platelet production time in major surgery is described. This was equated to the time taken for renewal of maximum malondialdehyde (MDA) activity in blood platelets following suppression by a single dose of aspirin (Stuart et al 1975). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f531fbc9e2eb0c7ba5545de6c16dc75
https://doi.org/10.1111/j.1600-0609.1981.tb01377.x

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Studies on the removal of abnormal prion protein by processes used in the manufacture of human plasma products

Autor: P R, Foster, A G, Welch, C, McLean, B D, Griffin, J C, Hardy, A, Bartley, S, MacDonald, A C, Bailey

Publikováno v: Vox sanguinis. 78(2)

To identify if any process steps used in plasma fractionation may have a capability of removing agents of human transmissible spongiform encephalopathy (TSE).Sixteen fractionation steps were investigated separately by adding a preparation of hamster

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39d0d7094971330e9f799cc33d00db4c
https://pubmed.ncbi.nlm.nih.gov/10765143

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Heparin-like activity in uterine fluid

Autor: J K Clayton, D. M. Jenkins, B D Griffin, M E Foley, M Zuzel, G P McNichol, C. C. Bird, S. M. Rajah, S.R. Aparicio, K. Bradbury, J S Scott

Publikováno v: BMJ. 2:322-324

Uterine fluid was collected from a group of normal patients and a group of patients with menorrhagia. Heparin-like activity was detected in 34 out of 38 samples using an anti-Xa heparin assay. The heparin-like activity in uterine fluid was inhibited

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983cc55a9d3d4c2a33779855ff6bc156
https://doi.org/10.1136/bmj.2.6133.322

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Immunoaffinity purification of factor VIII complex

Autor: V S, Hornsey, B D, Griffin, D S, Pepper, L R, Micklem, C V, Prowse

Publikováno v: Thrombosis and haemostasis. 57(1)

Murine monoclonal antibodies to human von Willebrand factor (vWf) were immobilised on Sephacryl S-1000. Various solutes were screened for their ability to elute 125I-vWf from the immobilised antibodies. The most effective solutions were then tested t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03795a7f31e66db10cff8a1921bf80f5
https://pubmed.ncbi.nlm.nih.gov/3109055

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The production and characterisation of a panel of ten murine monoclonal antibodies to human procoagulant factor VIII

Autor: B D, Griffin, L R, Micklem, M C, McCann, K, James, D S, Pepper

Publikováno v: Thrombosis and haemostasis. 55(1)

A panel of 10 murine monoclonal antibodies to procoagulant FVIII has been developed from the fusion of a single spleen. Balb/c mice were injected with a purified preparation of FVIII: Ag, and antibody production in sera and hybrid culture supernatant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1bba6cb000be9e9c97f274f564c6d59b
https://pubmed.ncbi.nlm.nih.gov/3085263

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