Zobrazeno 1 - 10
of 71
pro vyhledávání: '"B D, Pate"'
Publikováno v:
Medical Microbiology and Immunology. 188:161-168
Nocardia asteroides GUH-2 (GUH-2) invades the nigrostriatal region of the brain in mice [15]. Selective dopaminergic neuronal dropout in the substantia nigra results in parkinsonian changes characterized by movement disorders responsive to L-dopa [15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e617edd843c040b6a2129e2d3f0500aa
https://doi.org/10.1007/s004309900030
https://doi.org/10.1007/s004309900030
Autor:
James E. Holden, Donald B. Calne, B. D. Pate, Doris J. Doudet, K. Scott Morrison, Thomas J. Ruth, Grace L.-Y. Chan
Publikováno v:
European Journal of Pharmacology. 334:31-38
The consequences of monoamine oxidase and catechol-O-methyltransferase inhibition on the effective turnover of dopamine were investigated using 6-[ 18 F ] l -3-4-dihydroxyphenylalanine (6-[ 18 F ] l -DOPA) and positron emission tomography. The effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9d5f7a416ea05cbf044ca1c184be55
https://doi.org/10.1016/s0014-2999(97)01157-6
https://doi.org/10.1016/s0014-2999(97)01157-6
Autor:
Doris J. Doudet, B. D. Pate, Kellie A. Hewitt, Donald B. Calne, Daniel P. Perl, Barry J. Snow, W. Olanow, R. Nugent, Hitoshi Shinotoh
Publikováno v:
Neurology. 45:1199-1204
Using MRI and PET, we investigated the consequences of manganese intoxication in a primate model of parkinsonism and dystonia. Three rhesus monkeys were injected intravenously with doses of 10 to 14 mg/kg of MnCl2 on seven occasions, each a week apar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab834fc75b8f9c9af56125064a6ae1e
https://doi.org/10.1212/wnl.45.6.1199
https://doi.org/10.1212/wnl.45.6.1199
Publikováno v:
The Canadian Journal of Psychiatry. 35:684-688
Six subjects with DSM-III defined unipolar major depressive disorder had positron emission tomography scans using 18F-2-fluoro-2-deoxy-D-glucose (2FDG) before and after treatment with imipramine. Their 12 scans were compared to the scans of six contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829bce3aac26ff711823909c8bd080e1
https://doi.org/10.1177/070674379003500807
https://doi.org/10.1177/070674379003500807
Publikováno v:
European journal of pharmacology. 334(1)
The consequences of monoamine oxidase and catechol-O-methyltransferase inhibition on the effective turnover of dopamine were investigated using 6-[18F]L-3-4-dihydroxyphenylalanine (6-[18F]L-DOPA) and positron emission tomography. The effective dopami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf2c7eb9c6a76045d5af381f92eb4150
https://pubmed.ncbi.nlm.nih.gov/9346324
https://pubmed.ncbi.nlm.nih.gov/9346324
Graphical analysis of 6-fluoro-L-dopa trapping: effect of inhibition of catechol-O-methyltransferase
Autor:
J E, Holden, D, Doudet, C J, Endres, G L, Chan, K S, Morrison, F J, Vingerhoets, B J, Snow, B D, Pate, V, Sossi, K R, Buckley, T J, Ruth
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(10)
Graphical methods to analyze tracer time-course data allow reliable quantitation of the rate of incorporation of tracer from plasma into a "trapped" kinetic component, even when the details of the kinetic model are unknown. Applications of the method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b9556cdad9cc327526e64d191b719d0
https://pubmed.ncbi.nlm.nih.gov/9379194
https://pubmed.ncbi.nlm.nih.gov/9379194
Autor:
Grace L.-Y. Chan, B. D. Pate, Poppy Schofield, Kellie A. Hewitt, Teresa Dobko, Doris J. Doudet, Thomas J. Ruth
Publikováno v:
Life sciences. 56(21)
In 6-[18F]fluoro-L-dopa (Fdopa)/positron emission tomography (PET) studies, carbidopa pretreatment increases the Fdopa bioavailability to the brain and enhances the intensity of striatal PET images. Different PET research teams have used various carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a143c5e9f42b5e8d0b98d759059a797c
https://pubmed.ncbi.nlm.nih.gov/7739350
https://pubmed.ncbi.nlm.nih.gov/7739350
Autor:
B. D. Pate, Barry J. Snow, S. Cooper, Donald B. Calne, Thomas J. Ruth, Michael Schulzer, M. Cordes
Publikováno v:
Annals of neurology. 36(4)
Despite postmortem evidence for an age-related decline in nigrostriatal dopaminergic function, position emission tomography (PET) studies have produced inconsistent results. This may be due to differences in methods or of subject selection. To invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972b99bf9f2d43a9e8b4c1dd8a583840
https://pubmed.ncbi.nlm.nih.gov/7944302
https://pubmed.ncbi.nlm.nih.gov/7944302
Autor:
Thomas J. Ruth, B. D. Pate, Donald B. Calne, John P. Hammerstad, Kellie A. Hewitt, Grace L.-Y. Chan
Publikováno v:
Annals of neurology. 34(4)
The transport of L-6-fluorodopa and its major metabolites from the blood to the brain, cerebrospinal fluid (CSF), and muscle was studied in carbidopa-pretreated cynomolgus monkeys. A bolus intravenous injection of 18F-L-6-fluorodopa was followed by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba652b539f9d2d2484ad1736a54735b9
https://pubmed.ncbi.nlm.nih.gov/8215248
https://pubmed.ncbi.nlm.nih.gov/8215248
Autor:
Kellie A. Hewitt, B. D. Pate, Donald B. Calne, Edith G. McGeer, Barry J. Snow, T. Kawamata, Tatsuo Yamada, Thomas J. Ruth
Publikováno v:
Annals of neurology. 34(3)
Striatal 18F-6-fluorodopa (FD) uptake constants were measured by positron emission tomography in (1) normal cynomolgus monkeys and (2) a series of cynomolgus and rhesus monkeys that had received intracarotid infusions of 1-methyl-4-phenyl-1,2,3,6-tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be12f81127f7942c736df2202f44e55
https://pubmed.ncbi.nlm.nih.gov/8363350
https://pubmed.ncbi.nlm.nih.gov/8363350