Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells

Autor: D M, Bodine, T, Moritz, R E, Donahue, B D, Luskey, S W, Kessler, D I, Martin, S H, Orkin, A W, Nienhuis, D A, Williams

Publikováno v: Blood. 82:1975-1980

Retroviral mediated gene transfer into stem cells has been proposed as therapy for many inherited hematopoietic diseases. Deficiency of the enzyme adenosine deaminase (ADA) results in depletion of T lymphocytes, causing severe combined immunodeficien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5a1f4074561461b3628f99756a442f
https://doi.org/10.1182/blood.v82.7.1975.1975

Functional expression of human CD8 in fully reconstituted mice after retroviral-mediated gene transfer of hemopoietic stem cells

Autor: G A, Holländer, B D, Luskey, D A, Williams, S J, Burakoff

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 149(2)

Retroviral-mediated gene transfer has been used in an attempt to efficiently and stably express functional cell-surface molecules in lymphoid and myeloid cells. The human CD8 molecule is a T cell-specific surface receptor that is intimately involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c0754bb55019e268268bffa8052c708
https://pubmed.ncbi.nlm.nih.gov/1624791

Retroviral-mediated gene transfer of human adenosine deaminase into murine hematopoietic cells

Autor: J F, Apperley, B D, Luskey, D A, Williams

Publikováno v: Seminars in hematology. 28(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e524dbece886f5ba82263d19dab169d
https://pubmed.ncbi.nlm.nih.gov/1876864

Modular Synthesis of Azines Bearing a Guanidine Core from N-Heterocyclic Carbene (NHC)-Derived Selenoureas and Diazo Reagents.

Autor: Tonis E; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771, Athens, Greece., Tzouras NV; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771, Athens, Greece.; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Bracho Pozsoni N; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Saab M; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Bhandary S; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Van Hecke K; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Nelson DJ; WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland., Nahra F; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium.; VITO (Flemish Institute for Technological Research), Boeretang 200, 2400, Mol, Belgium., Nolan SP; Department of Chemistry and Centre of Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000, Ghent, Belgium., Vougioukalakis GC; Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771, Athens, Greece.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Sep 19; Vol. 30 (53), pp. e202401816. Date of Electronic Publication: 2024 Sep 03.

Clonal succession in the hemopoietic system: Number of primitive hemopoietic stem cells and clone lifespan.

Autor: Drize, N., Todriya, T., Chertkov, I.

Publikováno v: Bulletin of Experimental Biology & Medicine; Apr1999, Vol. 127 Issue 4, p381-385, 5p