Zobrazeno 1 - 8
of 8
pro vyhledávání: '"B D, Dayton"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 271:C869-C877
Endothelins (ET) are potent vasoconstricting peptides with 21 amino acid residues. Endothelin-1 (ET-1) stimulates arachidonic acid (AA) release in human pericardial smooth muscle cells (HPSMC), which is primarily mediated through the ETA receptor. Ma
Autor:
Stephen Condon, J R Luly, B G Donner, S A Boyd, Jerome Cohen, Anthony K. L. Fung, Herman H. Stein, B D Dayton, S H Rosenberg, William R. Baker
Publikováno v:
Clinical Chemistry. 38:2239-2243
To establish whether the use of proteinase inhibitors in the routine determination of in vitro plasma renin activity overestimates the potency of renin inhibitors in vivo, we examined the effects of phenylmethylsulfonyl fluoride and 8-hydroxyquinolin
Autor:
J R, Wu-Wong, J D, Alder, L, Alder, D J, Burns, E K, Han, B, Credo, S K, Tahir, B D, Dayton, P J, Ewing, W J, Chiou
Publikováno v:
Cancer research. 61(4)
A high-throughput screening assay was designed to select compounds that inhibit the growth of cultured mammalian cells. After screening more than 60,000 compounds, A-105972 was identified and selected for further testing. A-105972 is a small molecule
Publikováno v:
Receptorssignal transduction. 7(3)
Endothelins (ETs) are 21-amino acid peptides that bind to membrane receptors to initiate pathophysiological effects. This report characterizes ET receptors in benign prostatic hyperplasia-1 (BPH-1) cells, a prostate cell line isolated from a specimen
Autor:
T J, Opgenorth, A L, Adler, S V, Calzadilla, W J, Chiou, B D, Dayton, D B, Dixon, L J, Gehrke, L, Hernandez, S R, Magnuson, K C, Marsh, E I, Novosad, T W, Von Geldern, J L, Wessale, M, Winn, J R, Wu-Wong
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 276(2)
Endothelins (ET) are potent vasoactive peptides implicated in the pathogenesis of a number of vascular diseases. The effects of ET on mammalian organs and cells are initiated by binding to ETA or ETB receptors. In this report, we document the pharmac
Autor:
B D, Dayton, H H, Stein, J, Cohen, W R, Baker, S A, Boyd, S L, Condon, B G, Donner, A K, Fung, J R, Luly, S H, Rosenberg
Publikováno v:
Clinical chemistry. 38(11)
To establish whether the use of proteinase inhibitors in the routine determination of in vitro plasma renin activity overestimates the potency of renin inhibitors in vivo, we examined the effects of phenylmethylsulfonyl fluoride and 8-hydroxyquinolin
Publikováno v:
Cancer research. 42(3)
CC-1065, a novel antibiotic produced by Streptomyces zelensis, was active against several experimental tumors in vivo and a broad spectrum of human tumor cells in vitro. This report describes its biological and biochemical effects of L1210 leukemia c
Autor:
D H, Swenson, L H, Li, L H, Hurley, J S, Rokem, G L, Petzold, B D, Dayton, T L, Wallace, A H, Lin, W C, Krueger
Publikováno v:
Cancer research. 42(7)
CC-1065 (NSC 298223), a potent new antitumor antibiotic produced by Streptomyces zelensis, interacts strongly with double-stranded DNA and appears to exert its cytotoxic effects through disruption of DNA synthesis. We undertook this study to elucidat