Výsledky vyhledávání

Elevations in serum soluble interleukin-2 receptor levels predict relapse in patients with hairy cell leukemia

Autor: B, Arun, B D, Curti, D L, Longo, D, Stevens, W G, Alvord, B L, Gause, T, Watson, W C, Kopp, J E, Janik

Publikováno v: The cancer journal from Scientific American. 6(1)

Interferon-alfa, 2'-deoxycoformycin, and 2-chlorodeoxy-adenosine (2-CdA) are effective in the management of patients with hairy cell leukemia. These agents produce remissions in most patients, but relapses occur with all three drugs. The optimal mean

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::229cf3222117b9c9df1e4712b439f6b6
https://pubmed.ncbi.nlm.nih.gov/10696734

Zobrazit plný text záznamu

Abrogation of the hematological and biological activities of the interleukin-3/granulocyte-macrophage colony-stimulating factor fusion protein PIXY321 by neutralizing anti-PIXY321 antibodies in cancer patients receiving high-dose carboplatin

Autor: L L, Miller, E L, Korn, D S, Stevens, J E, Janik, B L, Gause, W C, Kopp, J T, Holmlund, B D, Curti, M, Sznol, J W, Smith, W J, Urba, S E, Donegan, T M, Watson, D L, Longo

Publikováno v: Blood. 93(10)

This dose-escalation study was performed to evaluate the hematologic activity, biological effects, immunogenicity, and toxicity of PIXY321 (an interleukin-3/granulocyte-macrophage colony-stimulating factor fusion protein) administered after high-dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32ce936eb3ac3958428383a72b17d6f2
https://pubmed.ncbi.nlm.nih.gov/10233876

Zobrazit plný text záznamu

Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycoformycin

Autor: J, Yoe, B L, Gause, B D, Curti, D L, Longo, A, Bagg, W C, Kopp, J E, Janik

Publikováno v: American journal of hematology. 57(3)

The association of T-cell large granular lymphocyte (LGL) leukemia and rheumatoid arthritis is well described and it is now recognized that these patients and patients with Felty's syndrome represent different aspects of a single disease process. Mos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53570fe3d8cb3eb301fcb12a34820312
https://pubmed.ncbi.nlm.nih.gov/9495380

Zobrazit plný text záznamu

Adoptive transfer of anti-CD3-activated CD4+ T cells plus cyclophosphamide and liposome-encapsulated interleukin-2 cure murine MC-38 and 3LL tumors and establish tumor-specific immunity

Autor: M L, Saxton, D L, Longo, H E, Wetzel, H, Tribble, W G, Alvord, L W, Kwak, A S, Leonard, C D, Ullmann, B D, Curti, A C, Ochoa

Publikováno v: Blood. 89(7)

The infusion of anti-CD3-activated murine T cells plus interleukin-2 (IL-2) exerts antitumor effects against several tumors in murine immunotherapy models. This study compares the therapeutic efficacy of anti-CD3-activated CD4+ or CD8+ T-cell subsets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c2af8369972c423d0379c5025f0cd76
https://pubmed.ncbi.nlm.nih.gov/9116299

Zobrazit plný text záznamu

A Brief History of Immunologic Thinking: Is it Time for Yin and Yang?

Autor: B. D. Curti, D. L. Longo

Publikováno v: A Survey of Models for Tumor-Immune System Dynamics ISBN: 9781461264088

Our understanding of tumor biology and the immune system has expanded greatly in the last decade. This explosion of knowledge can be attributed to advances in molecular biology. Despite these advances, our success in devising effective therapy agains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7529f6df0ce23503b0f2e0d2e2cc9aa0
https://doi.org/10.1007/978-0-8176-8119-7_1

Zobrazit plný text záznamu

Adoptive immunotherapy

Autor: B D, Curti

Publikováno v: Cancer chemotherapy and biological response modifiers. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::76857ef0acb7354887ce862da6c437cc
https://pubmed.ncbi.nlm.nih.gov/8639385

Zobrazit plný text záznamu

Alterations in T cell receptor and signal transduction molecules in melanoma patients

Autor: A H, Zea, B D, Curti, D L, Longo, W G, Alvord, S L, Strobl, H, Mizoguchi, S P, Creekmore, J J, O'Shea, G C, Powers, W J, Urba

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 1(11)

We have recently described molecular changes in T cells from tumor-bearing patients that are associated with depressed immune function. The present work investigates changes in T-cell signal transduction proteins including the T-cell receptor-zeta (T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf9b679e81a504eced51e585acafd495
https://pubmed.ncbi.nlm.nih.gov/9815928

Zobrazit plný text záznamu

Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients: changes during treatment

Autor: B D, Curti, W J, Urba, W G, Alvord, J E, Janik, J W, Smith, K, Madara, D L, Longo

Publikováno v: Cancer research. 53

Interstitial pressure (IP) is a physiological variable that may have its greatest influence on the transport of high-molecular-weight therapeutic agents. IP in tumor nodules was measured in patients with metastatic melanoma or non-Hodgkin's lymphoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::325f7855c953ff2852f237a1ebb3ed68
https://pubmed.ncbi.nlm.nih.gov/8485703

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání