Zobrazeno 1 - 10
of 416
pro vyhledávání: '"B Coffey"'
Autor:
Niall B. Coffey, Douglas R. MacAyeal, Luke Copland, Derek R. Mueller, Olga V. Sergienko, Alison F. Banwell, Ching-Yao Lai
Publikováno v:
Journal of Glaciology, Vol 68, Pp 867-878 (2022)
The once-contiguous Ellesmere Ice Shelf, first reported in writing by European explorers in 1876, and now almost completely disintegrated, has rolling, wave-like surface topography, the origin of which we investigate using a viscous buckling instabil
Externí odkaz:
https://doaj.org/article/c77e5abc48944c5fb2a12d0fb376c2d0
Autor:
Scott B Coffey
Publikováno v:
American Nurse Journal. 18:22-24
Establish a culture of patient safety focused on education, evidence-based protocols, and nonpunitive reporting.
Autor:
Lucrezia Zuccarelli, Letizia Galasso, Rachel Turner, Emily J. B. Coffey, Loredana Bessone, Giacomo Strapazzon
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Background: Successful long-duration missions outside low-Earth orbit will depend on technical and physiological challenges under abnormal environmental conditions. Caves, characterized by absence of light, confinement, three-dimensional human moveme
Externí odkaz:
https://doaj.org/article/7a4be20f831842bba3986b887a7ef993
Publikováno v:
Journal of the American Nutrition Association. 42:178-186
Endurance runners exhibit an elevated prevalence of low bone mass and characteristics consistent with undernourishment.This quasi-experimental, pretest-posttest design study evaluated the efficacy of a 4-week nutrition education curriculum to optimiz
Autor:
Hao Sun, David W Piotrowski, Suvi T M Orr, Joseph S Warmus, Angela C Wolford, Steven B Coffey, Kentaro Futatsugi, Yinsheng Zhang, Alfin D N Vaz
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206279 (2018)
Two chemotypes were examined in vitro with CYPs 3A4 and 2C19 by molecular docking, metabolic profiles, and intrinsic clearance deuterium isotope effects with specifically deuterated form to assess the potential for enhancement of pharmacokinetic para
Externí odkaz:
https://doaj.org/article/5eb59c1e4e2740a591ed41a6ec90eaa8
Autor:
Allyn T. Londregan, Karlygash Aitmakhanova, James Bennett, Laura J. Byrnes, Daniel P. Canterbury, Xiayun Cheng, Thomas Christott, Jennifer Clemens, Steven B. Coffey, João M. Dias, Matthew S. Dowling, Gillian Farnie, Oleg Fedorov, Kimberly F. Fennell, Vicki Gamble, Carina Gileadi, Charline Giroud, Michael R. Harris, Brett D. Hollingshead, Kilian Huber, Magdalena Korczynska, Kimberly Lapham, Paula M. Loria, Arjun Narayanan, Dafydd R. Owen, Brigitt Raux, Parag V. Sahasrabudhe, Roger B. Ruggeri, Laura Díaz Sáez, Ingrid A. Stock, Benjamin A. Thuma, Andy Tsai, Alison E. Varghese
Publikováno v:
Journal of medicinal chemistry.
A series of small-molecule YEATS4 binders have been discovered as part of an ongoing research effort to generate high-quality probe molecules for emerging and/or challenging epigenetic targets. Analogues such as
Autor:
Kentaro Futatsugi, Shawn Cabral, Daniel W. Kung, Kim Huard, Esther Lee, Markus Boehm, Jonathan Bauman, Ronald W. Clark, Steven B. Coffey, Collin Crowley, Anne-Marie Dechert-Schmitt, Matthew S. Dowling, Robert Dullea, James R. Gosset, Amit S. Kalgutkar, Kou Kou, Qifang Li, Yajing Lian, Paula M. Loria, Allyn T. Londregan, Mark Niosi, Christine Orozco, John C. Pettersen, Jeffrey A. Pfefferkorn, Jana Polivkova, Trenton T. Ross, Raman Sharma, Ingrid A. Stock, Gregory Tesz, Hanna Wisniewska, Bryan Goodwin, David A. Price
Publikováno v:
Journal of medicinal chemistry. 65(22)
Discovery efforts leading to the identification of ervogastat (PF-06865571), a systemically acting diacylglycerol acyltransferase (DGAT2) inhibitor that has advanced into clinical trials for the treatment of non-alcoholic steatohepatitis (NASH) with
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