Zobrazeno 1 - 10
of 88
pro vyhledávání: '"B Cell Follicle"'
Autor:
Florian L. Schwarzenberg, Paul Schütz, Jörg U. Hammel, Mirko Riedel, Jasmin Bartl, Sharareh Bordbari, Svea-Celina Frank, Bernd Walkenfort, Madleen Busse, Julia Herzen, Christian Lohr, Clemens Wülfing, Stephan Henne
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
With growing molecular evidence for correlations between spatial arrangement of blood vasculature and fundamental immunological functions, carried out in distinct compartments of the subdivided lymph node, there is an urgent need for three-dimensiona
Externí odkaz:
https://doaj.org/article/40aa944221fe4139bfcaa1ea66678891
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Human immunodeficiency virus (HIV) infection can be effectively suppressed by life-long administration of combination antiretroviral therapy (cART). However, the viral rebound can occur upon cART cessation due to the long-term presence of HIV reservo
Externí odkaz:
https://doaj.org/article/4acc12935ecf4fa6a416a52493f6d97c
Autor:
Matthew T. Ollerton, Joy M. Folkvord, Andriana La Mantia, David A. Parry, Amie L. Meditz, Martin D. McCarter, Richard T. D’Aquila, Elizabeth Connick
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Follicular helper CD4+ T cells (TFH) are highly permissive to HIV and major foci of virus expression in both untreated and treated infection. Follicular regulatory CD4+ T cells (TFR) limit TFH numbers and function in vitro and in vivo. We evaluated t
Externí odkaz:
https://doaj.org/article/3737dd4c5dd84da584fd3965bf4df15c
Autor:
An-Liang Guo, Yan-Mei Jiao, Qi-Wen Zhao, Hui-Huang Huang, Jian-Ning Deng, Chao Zhang, Xing Fan, Ruo-Nan Xu, Ji-Yuan Zhang, Cheng Zhen, Zhi-Man Xie, Ying-Mei Qin, Jian-Qing Xu, Yu Yang, Ming Shi, Lei Huang, Jin-Wen Song, Fu-Sheng Wang
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103794- (2022)
Summary: Background: B cell follicles are immune-privileged sites where intensive HIV-1 replication and latency occur, preventing a permanent cure. Recent study showed that CXCR5+ NK cells in B cell follicles can inhibit SIV replication in African gr
Externí odkaz:
https://doaj.org/article/bdccef29f9ad478c89ba15fa0da046fd
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T follicular regulatory cells, or Tfr cells, are a discernable population of regulatory T (Treg) cells that migrate to the B cell follicle and germinal center (GC) upon immune challenge. These cells express the transcription factor Bcl6, the master r
Externí odkaz:
https://doaj.org/article/22edeab0cda546b8b35f4e12389a3133
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
As we learn more about the HIV latent reservoir, we continue to discover that the viral reservoir is more complicated than just a pool of infected resting memory CD4+ T cells in peripheral blood. Evidence increasingly points to both certain tissues a
Externí odkaz:
https://doaj.org/article/ff0710f493cd42ea94ffb160ab63e02d
Autor:
Kristen M. Valentine, Katrina K. Hoyer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD8 T cells are infrequently considered part of germinal center reactions. Yet, a distinct CXCR5+ CD8 T cell subset identified within the B cell follicle and germinal center in situations of chronic antigen has recently been defined. CXCR5+ CD8 T cel
Externí odkaz:
https://doaj.org/article/e6284990d16147129319d6f84aa3d46b
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The majority of HIV replication occurs in secondary lymphoid organs (SLOs) such as the spleen, lymph nodes, and gut-associated lymphoid tissue. Within SLOs, HIV RNA+ cells are concentrated in the B-cell follicle during chronic untreated infection, an
Externí odkaz:
https://doaj.org/article/7fa22e2e2b874e3f9767ca263ca646fa
Autor:
Roberta Magliozzi, Richard Reynolds, Camilla Reali, Richard Nicholas, Federico Roncaroli, Owain W. Howell
Publikováno v:
Reali, C, Magliozzi, R, Roncaroli, F, Nicholas, R, Howell, O W & Reynolds, R 2020, ' B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis ', Brain Pathology . https://doi.org/10.1111/bpa.12841
Brain Pathology
Brain Pathology
Increased inflammation in the cerebral meninges is associated with extensive subpial cortical grey matter pathology in the forebrain and a more severe disease course in a substantial proportion of secondary progressive multiple sclerosis (SPMS) cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80335bce4b61e1915d57b2251f35cbc
https://doi.org/10.1111/bpa.12841
https://doi.org/10.1111/bpa.12841
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Human immunodeficiency virus (HIV) infects millions of people worldwide, and new cases continue to emerge. Once infected, the virus cannot be cleared by the immune system and causes acquired immunodeficiency syndrome. Combination antiretroviral thera
Externí odkaz:
https://doaj.org/article/9626c9b599d64039a411eb17ddfb390b