Výsledky vyhledávání

Diversification of exogenous genes in vivo in Neurospora

Autor: J. P. Rasmussen, David E. A. Catcheside, E. B. Cambareri, W. D. Stuart, J. Gabe, P. J. Yeadon, Frederick J. Bowring, E. Kato

Publikováno v: Applied Microbiology and Biotechnology. 62:544-549

We have adapted the meiotic recombination hotspot cog of Neurospora crassa for shuffling exogenous DNA, providing a means of generating novel genes in situ from sequences introduced into chromosomes. Genes to be diversified are inserted between the h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47233c268250d6d07523e290542e59b6
https://doi.org/10.1007/s00253-003-1327-2

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Simultaneous Antagonism of Interleukin-5, Granulocyte-Macrophage Colony-Stimulating Factor, and Interleukin-3 Stimulation of Human Eosinophils by Targetting the Common Cytokine Binding Site of Their Receptors

Autor: Q. Sun, K. Jones, B. McClure, B. Cambareri, B. Zacharakis, P.O. Iversen, F. Stomski, J.M. Woodcock, C.J. Bagley, R. D’Andrea, A.F. Lopez

Publikováno v: Blood. 94:1943-1951

Human interleukin-5 (IL-5), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-3 are eosinophilopoietic cytokines implicated in allergy in general and in the inflammation of the airways specifically as seen in asthma. All 3 cytokines f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184773ee9a287697d7bbdc20b5f58c84
https://doi.org/10.1182/blood.v94.6.1943

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The Neurospora transposon Tad is sensitive to repeat-induced point mutation (RIP)

Autor: E. B. Cambareri, P W Garrett-Engele, Eric U. Selker, John A. Kinsey

Publikováno v: Genetics. 138:657-664

RIP (repeat-induced point mutation) efficiently mutates repeated sequences in the sexual phase of the Neurospora crassa life cycle. Nevertheless, an active LINE-like retrotransposon, Tad, was found in a N. crassa strain from Adiopodoumé. The possibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12237fe7b564a9e06dcb659b809a5a08
https://doi.org/10.1093/genetics/138.3.657

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Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor

Autor: Joanna M. Woodcock, M F Shannon, Angel F. Lopez, Matthew A Vadas, B Cambareri, Christopher J. Bagley, M Dottore, T R Hercus

Publikováno v: Blood. 83:3500-3508

Residues within the first and fourth helices of human granulocyte- macrophage colony-stimulating factor (hGM-CSF) were analyzed for their role in biologic activity and interaction with the alpha- and beta- chains of the hGM-CSF receptor. Within the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc1cb143733c234b896e7cafbd7955cf
https://doi.org/10.1182/blood.v83.12.3500.3500

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Tadl-1, an active LINE-like element of Neurospora crassa

Autor: Edward B. Cambareri, John A. Kinsey, Jennifer Helber

Publikováno v: Molecular and General Genetics MGG. 242:658-665

Tad is a LINE-like retrotransposon of Neurospora crassa. The element was originally detected and cloned using the am gene as a transposon trap in hybrid strains derived from a cross of Adiopodoume (a wild collected strain) and a laboratory strain dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c87ef7cb2ad7b71cf896b0324b5968
https://doi.org/10.1007/bf00283420

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Allergic bronchopulmonary aspergillosis masquerading as pulmonary tuberculosis

Autor: Julia A. Clayton, Joseph B. Domachowske, Kevin G. Ragosta, Carol B. Cambareri

Publikováno v: The Pediatric infectious disease journal. 23(6)

We present an unusual pediatric patient with severe allergic bronchopulmonary aspergillosis that masqueraded as pulmonary tuberculosis. After antituberculous therapy, the patient's pulmonary disease flared, prompting an aggressive diagnostic evaluati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88aee9152b64b7186f76b07653d4c62c
https://pubmed.ncbi.nlm.nih.gov/15194847

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DNA methylation inhibits expression and transposition of the Neurospora Tad retrotransposon

Autor: John A. Kinsey, Y Zhou, E B Cambareri

Publikováno v: Molecular genetics and genomics : MGG. 265(4)

Tad is a LINE-like retrotransposon of the filamentous fungus Neurospora crassa. We have analyzed both expression and transposition of this element using strains with a single copy of Tad located in the 5' noncoding sequences of the am (glutamate dehy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943d9fbf2a9188b52be13cb8be0415fd
https://pubmed.ncbi.nlm.nih.gov/11459196

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Structure of the Chromosome VII Centromere Region in Neurospora crassa: Degenerate Transposons and Simple Repeats

Autor: Edward B. Cambareri, Rafael Aisner, John Carbon

Centromeres are regions of chromosomes that direct formation of the kinetochore and its subsequent attachment to the spindle, enabling the faithful segregation of the genetic material during cell division. This chromosomal domain, found in all eukary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec728936b20127151b67ae5bf789089
https://europepmc.org/articles/PMC109131/

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Tad1-1, an active LINE-like element of Neurospora crassa

Autor: E B, Cambareri, J, Helber, J A, Kinsey

Publikováno v: Moleculargeneral genetics : MGG. 242(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e52fcb27e5101b0eb370cbf47b39f19d
https://pubmed.ncbi.nlm.nih.gov/7512193

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